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Amantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Synonyms: 1-adamantanamine, 1-adamantylamineMixtures: Innoprax-5, ROSEL-TNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment … Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and
Categories: Heterocyclic Compounds, 1-Ring, ofloxacin and nitazoxanideProducts: VIBATRIN® 100 MG / 5 ML, ZELIX® 100 MG/ 5 MLAbciximab
go.drugbank.com/drugs/DB00054ApprovedWithdrawnAbciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. … It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells.
Categories: Amino Acids, Peptides, and Proteins, Blood and Blood Forming OrgansProducts: CLOTİNAB 10 MG/5 ML IV ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN FLAKON, 1 ADET, ReoPro 2 mg/ml Injektionslösung oder InfusionslösungZiritaxestat
go.drugbank.com/drugs/DB15403InvestigationalZiritaxestat is under investigation in clinical trial NCT03798366 (A Clinical Study to Test How Effective and Safe GLPG1690 is for Patients With Systemic Sclerosis).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)-piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)-(methyl)amino)-4-(4-fluorophenyl)-thiazole-5-carbonitrileUrsodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigational[A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid. … Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme InducersSynonyms: (3α,5β,7β)-3,7-dihydroxycholan-24-oic acidTeicoplanin
go.drugbank.com/drugs/DB06149ApprovedInvestigationalWithdrawnTeicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). … All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine moiety.
Categories: Amino Acids, Peptides, and ProteinsProducts: Teicoplanin Sandoz 100 mg – Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung oder einer Lösung zum Einnehmen, Teicoplanin AptaPharma 200 mg Pulver und Lösungsmittel zur Herstellung einer Injektions-/InfusionslösungN-[(2S,3S)-4-[2-[(5S)-3a,4,5,6,7,7a-Hexahydro-1,3-benzodioxol-5-yl]ethyl-[3-(1,3-dioxoisoindol-2-yl)propanoyl]amino]-3-hydroxy-1-phenylbutan-2-yl]-3,5-dimethoxy-4-phenylmethoxybenzamide
go.drugbank.com/drugs/DB03063ExperimentalSynonyms: N-[(2S,3S)-4-[2-[(5S)-3a,4,5,6,7,7a-Hexahydro-1,3-benzodioxol-5-yl]ethyl-[3-(1,3-dioxoisoindol-2-yl)propanoyl]amino]-3-hydroxy-1-phenylbutan-2-yl]-3,5-dimethoxy-4-phenylmethoxybenzamideGonadorelin
go.drugbank.com/drugs/DB00644ApprovedInvestigationalVet approvedIt is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary.
Mixtures: Relisorm 100 for Inj.-pws Liq-kit Sc IVCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsCisplatin
go.drugbank.com/drugs/DB00515ApprovedInvestigationalcancer, and ovarian cancer), lymphomas and germ cell tumors. … Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung
Categories: Indicators and Reagents, Antineoplastic and Immunomodulating AgentsSynonyms: (SP-4-2)-DIAMMINEDICHLOROPLATINUM, PLATINUM, DIAMMINEDICHLORO-, (SP-4-2)-Cetuximab
go.drugbank.com/drugs/DB00002ApprovedInvestigational[A227963] EGFR is often mutated in certain types of cancer and serves as a driver of tumorigenesis. … [A227973] EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible for regulating epithelial tissue development and homeostasis.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: ERBITUX ® 5 MG/ML, ERBITUX® 5 MG/ML