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Miltefosine
go.drugbank.com/drugs/DB09031ApprovedInvestigationalIt can be administered topically or orally and is only indicated in patients aged 12 years or older. … It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease.
Categories: Agents Against Leishmaniasis and Trypanosomiasis, Antiparasitic Products, Insecticides and RepellentsPeppermint oil
go.drugbank.com/drugs/DB11198ApprovedInvestigationalExtracted from the stem, leaves, and flowers of _Mentha piperita_ L. plant, peppermint oil (Mentha piperita) is a popular essential oil used in aromatherapy for both external and internal use. … Due to its effectiveness in relaxing GI smooth muscle but ability to induce gastroesophageal reflux, enteric-coated formulations of peppermint oil has been established which bypass the upper GI tract unmetabolized
Categories: Alimentary Tract and Metabolism, Herbs and Natural ProductsZinc transporter ZIP11
go.drugbank.com/bio_entities/BE0009906TransporterHumansZinc importer that regulates cytosolic zinc concentrations either via zinc influx from the extracellular compartment or efflux from intracellular organelles such as Golgi apparatus.
Synonyms: Zrt- and Irt-like protein 11Protein phosphatase 1 regulatory subunit 15A
go.drugbank.com/bio_entities/BE0011888TargetHumansfacilitating recovery of cells from stress (PubMed:26095357, PubMed:26742780). … Plays an essential role in autophagy by tuning translation during starvation, thus enabling lysosomal biogenesis and a sustained autophagic flux (PubMed:32978159).
Synonyms: Growth arrest and DNA damage-inducible protein GADD34Acamprosate
go.drugbank.com/drugs/DB00659ApprovedInvestigationalAlcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, … It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783]
Vidarabine
go.drugbank.com/drugs/DB00194ApprovedWithdrawnA nucleoside antibiotic isolated from Streptomyces antibioticus. … It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the
Categories: Nucleic Acids, Nucleotides, and Nucleosides, Nucleosides and Nucleotides Excl. Reverse Transcriptase InhibitorsStrontium chloride Sr-89
go.drugbank.com/drugs/DB09498ApprovedStrontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. … It is usually presented mainly in patients with prostatic and breast cancer, as well as in cancer of lung, bladder and thyroid.
Wart Viral
go.drugbank.com/conditions/DBCOND0140696Drugs: DiphencyproneSynonyms: Viral wart of skin and/or mucous membrane caused by human papillomavirus, Viral wart of skin and/or mucous membrane caused by human papillomavirus (disorder)Fosphenytoin
go.drugbank.com/drugs/DB01320ApprovedInvestigationalIts main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials. … It works by slowing down impulses in the brain that cause seizures.
Categories: Phenytoin and ProdrugsMavorixafor
go.drugbank.com/drugs/DB05501ApprovedInvestigationalby a reduced number of mature neutrophils and lymphocytes. … [L50642] It was first approved by the FDA on April 30, 2024, for the treatment of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome, a genetic immunodeficiency disorder characterized
Categories: Antineoplastic and Immunomodulating Agents