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Alginic acid
go.drugbank.com/drugs/DB13518ApprovedInvestigationalWithdrawnAlginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (_Phacophycae_) via alkaline extraction. … It is also available in oral dietary supplements and is found in antacids such as Gaviscon to inhibit gastroesophageal reflux by creating a physical barrier in presence of gastric acid [F46].
Mixtures: Zinc and Algin Tab Nu Life, MILACID® SACHET POR 10ML SABOR MENTACategories: Alimentary Tract and Metabolism, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Epcoritamab
go.drugbank.com/drugs/DB16672ApprovedInvestigationalAlthough this regimen is effective in up to 60% of patients, patients with relapsed or refractory DLBCL have poor outcomes. … [A259736,A258488,A259761,L46516] Epcoritamab promotes the activation and expansion of T-cells and, by being able to bind to both CD20 and CD3, it leads to the T-cell–mediated killing of CD20+ malignant
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsFlurandrenolide
go.drugbank.com/drugs/DB00846ApprovedIt is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive. (From Martindale, The Extra Pharmacopoeia, 30th ed, p733)
Categories: fludroxycortide and antibiotics, Hormones, Hormone Substitutes, and Hormone AntagonistsScorpion (centruroides) immune Fab2 antivenin (equine)
go.drugbank.com/drugs/DB13905ApprovedIt was approved by FDA in 2011 and is marketed under the name Anascorp [L2196]. Anascorp is produced from equine IgG antibodies. … Because initial development and use of this product in Mexico, venoms from several Centruroides species endemic to Mexico are pooled and diluted [L2207].
BAX 335
go.drugbank.com/drugs/DB17845InvestigationalBAX 335 is an adeno-associated virus vector 8 (AAV8)–based FIX gene therapy being investigated for the treatment of hemophilia B.[A259791]
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: An Adeno-Associated Virus Serotype 8 (AAV8) Vector Expressing FIX Padua (AAV8.ss-3xCRM8-TTRFIX_R338Lopt)Ethiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalAnd although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown. … Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil.
Tideglusib
go.drugbank.com/drugs/DB12129ApprovedInvestigationalWithdrawn[A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012. … Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy.
Zinc transporter ZIP11
go.drugbank.com/bio_entities/BE0009906TransporterHumansZinc importer that regulates cytosolic zinc concentrations either via zinc influx from the extracellular compartment or efflux from intracellular organelles such as Golgi apparatus.
Synonyms: Zrt- and Irt-like protein 11Protein phosphatase 1 regulatory subunit 15A
go.drugbank.com/bio_entities/BE0011888TargetHumansfacilitating recovery of cells from stress (PubMed:26095357, PubMed:26742780). … Plays an essential role in autophagy by tuning translation during starvation, thus enabling lysosomal biogenesis and a sustained autophagic flux (PubMed:32978159).
Synonyms: Growth arrest and DNA damage-inducible protein GADD34Strontium chloride Sr-89
go.drugbank.com/drugs/DB09498ApprovedStrontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. … It is usually presented mainly in patients with prostatic and breast cancer, as well as in cancer of lung, bladder and thyroid.