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Displaying results 2501 - 2510 of 3180 in total
  1. Drug

    Cobalt chloride

    go.drugbank.com/drugs/DB14206
    Approved

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  2. Drug

    Echinacea

    go.drugbank.com/drugs/DB14240
    ApprovedInvestigational

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  3. Drug

    Saw palmetto

    go.drugbank.com/drugs/DB14360
    ApprovedInvestigational

    Saw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  4. Drug

    Hydrocortisone phosphate

    go.drugbank.com/drugs/DB14542
    ApprovedInvestigationalVet approved

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers
  5. Drug

    Ivosidenib

    go.drugbank.com/drugs/DB14568
    ApprovedInvestigational

    Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, b...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  6. Drug

    Prednisolone hemisuccinate

    go.drugbank.com/drugs/DB14633
    Investigational

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  7. Drug

    Daridorexant

    go.drugbank.com/drugs/DB15031
    ApprovedInvestigational

    Daridorexant, formerly known as nemorexant, is a selective dual orexin receptor antagonist used to treat insomnia. Insomnia is characterized by difficulties with sleep onset and/or sleep maintenance and impairment of daytime functioning....

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Mipicoledine

    go.drugbank.com/drugs/DB15075
    Investigational

    Mipicoledine is under investigation in clinical trial NCT01048008 (Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer).

    Categories: P-glycoprotein substrates
  9. Drug

    Upadacitinib

    go.drugbank.com/drugs/DB15091
    ApprovedInvestigational

    Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmu...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  10. Drug

    Tepotinib

    go.drugbank.com/drugs/DB15133
    ApprovedInvestigational

    Tepotinib is a MET tyrosine kinase inhibitor intended to treat a variety of MET-overexpressing solid tumors. It was originally developed in partnership between EMD Serono and the University of Texas M.D. Anderson Cancer Center in 2009 an...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates