Prednisolone hemisuccinate

DB14633InvestigationalSmall molecule

Prednisolone hemisuccinate is a corticosteroid indicated in the treatment of anaphylaxis, asthma, edema, organ rejection, and other indications. A medication used to treat a wide variety of conditions including allergic reactions, swelling organs, and rejection of organ transplants.

Chemical structure of Prednisolone hemisuccinate
Formula / weight
C25H32O8 · 460.523 g/mol (avg)
Also known as
Prednisolone 21-succinate · Prednisolone bisuccinate · Prednisolone hydrogen succinate · Prednisolone succinate

Resolves to

Compound
UNIIG7080T74ONCAS2920-86-7ChEMBLCHEMBL485659ChEBI135745
Structure
InChIKeyAPGDTXUMTIZLCJ-CGVGKPPMSA-NSMILES[H][C@@]12CC[C@](O)(C(=O)COC(=O)CCC(O)=O)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

What you can answer from here — as of September 21, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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807Drug interactionsStructured to mechanism, not free text
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12Structured indicationsCondition, population, route and combination as fields, not prose
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1ContraindicationEach with its own population and attribute set
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10Marketed productsAcross 1 country and 2 labellers
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5+ReferencesStructured and connected to the statements they support
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Which other approved drugs treat the same conditions as Prednisolone hemisuccinate, and which companies have late-stage candidates in those indications?

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