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Displaying results 2521 - 2530 of 8696 in total
  1. Target

    Taste receptor type 2 member 10

    go.drugbank.com/bio_entities/BE0020463
    TargetHumans

    Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.

    Polypeptides: Taste receptor type 2 member 10Synonyms: Taste receptor family B member 2
  2. Target

    Short transient receptor potential channel 4

    go.drugbank.com/bio_entities/BE0020751
    TargetHumans

    Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:11042129, PubMed:11713258, PubMed:16144838, PubMed:39478185).

    Polypeptides: Short transient receptor potential channel 4
  3. Target

    Short transient receptor potential channel 5

    go.drugbank.com/bio_entities/BE0021113
    TargetHumans

    Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:16284075, PubMed:38959890, PubMed:37137991).

    Polypeptides: Short transient receptor potential channel 5Synonyms: Transient receptor protein 5
  4. Target

    Taste receptor type 2 member 14

    go.drugbank.com/bio_entities/BE0023216
    TargetHumans

    Gustducin-linked G protein-coupled receptor that plays a role in the perception of bitterness (PubMed:38600377, PubMed:38776963). … The activity of this receptor stimulates GNAT3, activating the gustducin G protein pathway (PubMed:38600377, PubMed:38776963).

    Polypeptides: Taste receptor type 2 member 14Synonyms: Taste receptor family B member 1
  5. Drug

    Idebenone

    go.drugbank.com/drugs/DB09081
    ApprovedInvestigational

    Due to its biochemical mode of action, it's thought that idebenone may re-activate viable-but-inactive retinal ganglion cells (RGCs) in LHON patients [L885]. … Lack of improvement in cognitive function halted its production for these conditions, however it continues to be investigated for use in other conditions associated with mitochondrial damage.

    Categories: Psychostimulants, Agents Used for ADHD and NootropicsSynonyms: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone
  6. Drug

    Foreskin keratinocyte (neonatal)

    go.drugbank.com/drugs/DB10772
    Approved

    Skin, the largest organ of the human body, plays the main role in protecting the body from mechanical damage. It is composed of epidermal, dermal and hypodermal layers. … Foreskin keratinocytes are an important ingredient in several skin substitutes [L2460], used for various indications.

  7. Drug

    Prednisolone

    go.drugbank.com/drugs/DB00860
    ApprovedInvestigationalVet approved

    Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.

    Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Corticosteroids for Systemic UseProducts: P-PRED
  8. Drug

    Naloxegol

    go.drugbank.com/drugs/DB09049
    ApprovedInvestigational

    The advantage of naloxegol over the opioid antagonist naloxone is that its PEGylated structure allows for high selectivity for peripheral opioid receptors and lack of entry into the central nervous system … Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca.

    Categories: Drugs for Constipation, Peripheral Opioid Receptor Antagonists
  9. Drug

    Cefalotin

    go.drugbank.com/drugs/DB00456
    ApprovedVet approvedWithdrawn

    Cefalotin is a cephalosporin antibiotic.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  10. Drug

    Cefmetazole

    go.drugbank.com/drugs/DB00274
    Approved

    It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use