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SYNB1020
go.drugbank.com/drugs/DB17667InvestigationalSYNB1020 is an engineered strain of _Escherichia coli_ Nissle 1917 developed by Synlogic Inc. … discontinued further development of SYNB1020 to treat hyperammonemia due to a lack of evidence of ammonia-lowering activities by SYNB1020 in a Phase 1b/2a study.
Roxatidine acetate
go.drugbank.com/drugs/DB08806InvestigationalRoxatidine acetate is a specific and competitive H2 receptor antagonist. It is currently approved in South Africa under the tradename Roxit.
Vedolizumab
go.drugbank.com/drugs/DB09033ApprovedInvestigational[L48216] Vedolizumab was developed by Takeda and approved by the FDA under the brand name ENTYVIO for the maintenance therapy of moderately to severely active Ulcerative Colitis and Crohn’s Disease … of vedolizumab against α4β7 integrin has been thought to contribute to its more favorable safety profile compared to its predecessor natalizumab, the first integrin receptor antagonist approved by the FDA
Butabarbital
go.drugbank.com/drugs/DB00237ApprovedIllicitWithdrawn[A201977,A201980] Butabarbital was granted FDA approval on 5 June 1939.[L13613]
Nebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigational[A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985]
Bopindolol
go.drugbank.com/drugs/DB08807ExperimentalBopindolol (INN) is an ester prodrug for the beta blocker [pindolol].
Estetrol
go.drugbank.com/drugs/DB12235ApprovedInvestigational[L33184] Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. … [L33184] On April 15 2021, Mayne Pharma Group Limited and Mithra Pharmaceuticals were granted FDA approval for the oral contraceptive Estelle/Nextstellis, a combination of [drospirenone] and estetrol
Chaetomium globosum
go.drugbank.com/drugs/DB10430ApprovedChaetomium globosum is a fungus which can provoke allergic reactions. Chaetomium globosum extract is used in allergenic testing.
Cladosporium sphaerospermum
go.drugbank.com/drugs/DB10432ApprovedCladosporium sphaerospermum is a fungus which can provoke allergic reactions. Cladosporium sphaerospermum extract is used in allergenic testing.
Ustilago tritici
go.drugbank.com/drugs/DB10444ApprovedUstilago tritici is a fungus which can provoke allergic reactions. Ustilago tritici extract is used in allergenic testing.