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Fosdenopterin
go.drugbank.com/drugs/DB16628Approved[A230088] Signs and symptoms begin shortly after birth and are caused by a build-up of toxic sulfites resulting from a lack of SOX activity. … Molybdenum cofactor deficiency (MoCD) is an exceptionally rare autosomal recessive disorder resulting in a deficiency of three molybdenum-dependent enzymes: sulfite oxidase (SOX), xanthine dehydrogenase
Categories: Alimentary Tract and Metabolism, Various Alimentary Tract and Metabolism ProductsTixagevimab
go.drugbank.com/drugs/DB16394ApprovedInvestigational[L39411] EVUSHELD was granted marketing authorization by the EMA on March 28, 2022,[L41454] and was approved in Canada soon after, on April 14, 2022. … [A243351, A243361, L39411] Tixagevimab is not approved for any indication by the FDA.
Categories: tixagevimab and cilgavimab, Amino Acids, Peptides, and ProteinsOsilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigationalCushing's disease),[A191850] and was granted FDA approval and Orphan Drug designation in the US in March 2020 for the same indication.[L12162] … [L12123] It has undergone phase II clinical trials for the treatment of solid tumours, hypertension, and heart failure, but development for these indications was discontinued by Novartis in January 2013
Categories: Sex Hormones and InsulinsDutasteride
go.drugbank.com/drugs/DB01126ApprovedInvestigationalIt is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. … Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart.
Synonyms: (5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamideMixtures: Dutasteride and tamsulosin hydrochloride, Dutasteride and Tamsulosin HydrochloridessCART-19 cells
go.drugbank.com/drugs/DB18653InvestigationalssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).
Synonyms: autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6) (also termed ssCART-19 cells)Ethiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalAnd although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown. … Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil.
Categories: Compounds used in a research, industrial, or household settingPsychophysiological Disorders
go.drugbank.com/conditions/DBCOND0172355Drugs: MelperoneSynonyms: Psychosomatic factor in physical condition, NOS, Psychosomatic factor in physical condition (finding)L-Glutamine
go.drugbank.com/drugs/DB00130ApprovedInvestigationalNutraceuticalAn oral formulation of L-glutamine was approved by the FDA in July 2017 for use in sickle cell disease [L892]. This oral formulation is marketed under the tradename Endari by Emmaus Medical. … It is the principal carrier of nitrogen in the body and is an important energy source for many cells.
Categories: Amino Acids and Derivatives, Alimentary Tract and MetabolismIodide I-123
go.drugbank.com/drugs/DB09420ApprovedInvestigationalFollowing oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland. … Radioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared
Salts: Sodium iodide I-123Synonyms: Iodide ion i-123, I 123Seizure Disorder, Post Traumatic
go.drugbank.com/conditions/DBCOND0106759Drugs: PhenytoinSynonyms: Epilepsy due to and following traumatic brain injury, Epilepsy due to and following traumatic brain injury (disorder)