Iodide I-123 is a radiopharmaceutical diagnostic agent used for the evaluation of the thyroid function and/or morphology. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland.
- Mechanism
- Curator reviewed
Sodium Iodide I-123 is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland. After incorporation, a gamma camera is used to detect the decay by electron capture to tellurium-123. Iodine is commonly used in thyroid function diagnostic tests as this gland normally absorbs iodine through the diet for formation of the thyroid hormones triiodothyronine (T3) and its prohormone, thyroxine (T4).
- Primary indication
- Administration of Sodium Iodide I 123 Capsules is indicated as a diagnostic procedure to be used in evaluating thyroid function and/or morphology.Curator reviewed · 2 structured indications
- Formula / weight
- I · 122.9061 g/mol (avg)
- First approval
- United States, 2003
- Also known as
- 123I− · I 123 · I-123 · I123 · Iodine 123
Resolves to
XMBWDFGMSWQBCA-AHCXROLUSA-MSMILES[123I-]What you can answer from here — as of September 23, 2026
Which drugs share a target with Iodide I-123, and which of those have an active Phase 3 trial?
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