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Displaying results 2531 - 2540 of 10000 in total
  1. Drug

    Apitegromab

    go.drugbank.com/drugs/DB16096
    ApprovedInvestigational

    motor neuron 2 (SMN2)-targeted therapy rather than in place of it. … Apitegromab-mstn is a fully human IgG4 lambda monoclonal antibody produced by recombinant DNA technology in Chinese Hamster Ovary cells.

    Synonyms: Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk-015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda.-chain, dimer
  2. Drug

    Tiazofurine

    go.drugbank.com/drugs/DB13243
    Experimental

    Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase [A174991].

    Synonyms: 2-(β-D-ribofuranosyl)-4-thiazolecarboxamide, 2-β-D-ribofuranosyl-4-thiazolecarboxamide
  3. Drug

    SKF-96365 free base

    go.drugbank.com/drugs/DB17054
    Experimental

    SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.[A253132]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole
  4. Drug

    DM-1157

    go.drugbank.com/drugs/DB18600
    Investigational

    Synonyms: 4-quinolinamine, 7-chloro-n-(3-(4-((di-2-pyridinylmethyl)amino)-1-piperidinyl)propyl)-
  5. Drug

    JNJ-28312141

    go.drugbank.com/drugs/DB17140
    Experimental

    Synonyms: 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide, 1h-imidazole-2-carboxamide, 5-cyano-n-(2-(1-cyclohexen-1-yl)-4-(1-(2-(dimethylamino)acetyl)-4-piperidinyl)phenyl)-Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Spebrutinib

    go.drugbank.com/drugs/DB11764
    Investigational

    Spebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(5-FLUORO-2-(4-(2-METHOXYETHOXY)PHENYLAMINO)PYRIMIDIN-4-YLAMINO)PHENYL)ACRYLAMIDE, N-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamide
  7. Drug

    Sutezolid

    go.drugbank.com/drugs/DB11905
    Investigational

    Sutezolid has been used in trials studying the treatment of Tuberculosis.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: ACETAMIDE, N-((3-(3-FLUORO-4-(4-THIOMORPHOLINYL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL)-, (S)-, N-{[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
  8. Drug

    Aminoflavone

    go.drugbank.com/drugs/DB19077
    Investigational

    Aminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 4h-1-benzopyran-4-one, 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-, 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-4h-1-benzopyran-4-one
  9. Drug

    4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID

    go.drugbank.com/drugs/DB06990
    Experimental

    Synonyms: 4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID
  10. Drug

    Guanosine

    go.drugbank.com/drugs/DB02857
    Investigational

    Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. … Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate) which are factors in signal

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one, 2(3H)-imino-9-β-D-ribofuranosyl-9H-purin-6(1H)-one