Search
Doxapram
go.drugbank.com/drugs/DB00561ApprovedInvestigationalVet approvedA central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Synonyms: 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinoneInternational brands: Dai Er SongDihydrocodeine
go.drugbank.com/drugs/DB01551ApprovedIllicitIt is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis … It was marketed in 1911.
Mixtures: Poly-tussin EX, J-cof DhcCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCanrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnLike spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Products: Aldactone 200 mg/ 10 ml Injektionslösung, POTASSIO CANRENOATO EGTirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalIt is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation. … Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery.
Synonyms: (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid, N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosineProducts: AGRASEL 12.5 MG/50 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON, 1 ADET, TIROSTU 12.5 MG/50 ML IV KONSANTRE İNFÜZYONLUK ÇÖZELTİ, 1 ADETChlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnIt is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Synonyms: ETHENAMINE, 2-(1-(4-CHLOROPHENYL)-1-PHENYLETHOXY)-N,N-DIMETHYL-, 2-((P-CHLORO-.ALPHA.-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-N,N-DIMETHYLETHYLAMINEMixtures: SISTRAL C DRAJE , 20 ADETTrastuzumab
go.drugbank.com/drugs/DB00072ApprovedInvestigationalIt is suggested that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and elevated activation of HER2 triggers multiple downstream pathways leading to abnormal … [L14015] It is used as a treatment of human epidermal growth factor receptor (HER)-2+ metastatic breast cancer, where there is a proven amplification of the HER-2 oncogene or over-expression of the HER
Mixtures: PHESGO® 1200 MG/600 MG, PHESGO® 1200 MG/600 MGCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsEdoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigational(PE) following 5-10 days of initial therapy with a parenteral anticoagulant. … It is indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesProducts: LIXIANA 15 MG FILM KAPLI TABLET ,10 TABLET, LIXIANA 15 MGCalcium gluconate
go.drugbank.com/drugs/DB11126ApprovedInvestigationalVet approvedEach 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate. … Each mL contains: Calcium gluconate 94 mg; calcium saccharate (tetrahydrate) 4.5 mg; water for injection q.s.
Synonyms: D-gluconic acid, calcium salt (2:1)Mixtures: CALPİNES 225 MG/10 ML + 572 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, CALCİLES 225 MG+572 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADETTrimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigational[A233215] It is hypothesized that trimetazidine inhibits 3-ketoacyl coenzyme A thiolase, which decreases fatty acid oxidation but not glucose metabolism, preventing the acidic conditions that exacerbate … However, it has been approved in France since 1978.[L33020]
Synonyms: 1-[2,3,4-trimethoxybenzyl] piperazine dihydrochlorideInternational brands: Vastarel MRDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [L6454] It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsSynonyms: (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine, (S)-duloxetine