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Tofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. … It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: JANTY 5 MG FİLM KAPLI TABLET, 56 ADET, TOFİK 5 MG FİLM KAPLI TABLET, 56 ADETLevofloxacin
go.drugbank.com/drugs/DB01137ApprovedInvestigational[A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and several South American countries soon after.[A190663] … Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin].
Mixtures: TRILEVO 500 MG+30 MG+ 1000 MG TEDAVİ PAKETİCategories: 4-Quinolones, MATE 1 InhibitorsCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin … It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to [DB00169] (vitamin D3) in the skin, which is then converted
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 1-alpha-25-Dihydroxyvitamin D3, (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triolZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.
Mixtures: N/A, COMBİVİR 150 MG/300 MG FİLM KAPLI TABLETCategories: Antivirals used in combination for the treatment of HIV infections, Cytochrome P-450 SubstratesFerric carboxymaltose
go.drugbank.com/drugs/DB08917ApprovedInvestigationalFerric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Categories: Compounds used in a research, industrial, or household settingProducts: Ferapplic 500 mg/10 ml Enjeksiyonluk/İnfüzyonluk Çözelti, 5 flakon, Ferinject® 50 mg iron/mL solution for injection/infusionAtracurium besylate
go.drugbank.com/drugs/DB00732ApprovedA non-depolarizing neuromuscular blocking agent with short duration of action. … Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents
Categories: Heterocyclic Compounds, 2-RingProducts: DEMATRAC 50 MG/5 ML İNFÜZYON İÇİN SOLÜSYON İÇEREN AMPUL, 10 AMPUL, ATRASYL 50 MG/5 ML I.V. ENJEKSIYON VE INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL , 10 AMPULDolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigationalDolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). … [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named
Mixtures: TRIUMEQ® 50 MG / 600 MG / 300 MG, TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLETCategories: Antivirals used in combination for the treatment of HIV infections, MATE 1 InhibitorsVericiguat
go.drugbank.com/drugs/DB15456ApprovedInvestigationalVericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. … to its structure have dramatically decreased its susceptibility to oxidative metabolism,[A227458] resulting in a relatively long half-life and allowing for once-daily dosing.
Categories: Vasodilators Used in Cardiac Diseases, P-glycoprotein substratesProducts: VERQUVO 5 MG FİLM KAPLI TABLET , 14 ADET, VERQUVO 5 MG FİLM KAPLI TABLET , 28 ADETDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigational[A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957. … Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse.
Mixtures: BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 ML, Poly-Vent DMCategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Sigma-1 AgonistPotassium citrate
go.drugbank.com/drugs/DB09125ApprovedInvestigationalVet approvedIn the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. … Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste.
Mixtures: PEDIALYTE®30MEQ CON ZN, Calcium-magnesium With K & Zn and Vitamin D3Products: CITRAL SYRUP (PLAIN) 500 mg/5 ml, UROCIT-K(5 MEQ) 540 MG 100 KONTROLLU SALIM TABLETI