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Floxuridine
go.drugbank.com/drugs/DB00322ApprovedInvestigationalIt has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Reserpine
go.drugbank.com/drugs/DB00206ApprovedWithdrawnThe FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 mg of reserpine.[L43942] … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Papaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalThe mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels. … An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions.
Products: PAPAVERINE HCL 60 MG TABLET, 20 ADET, PAPAVERIN HCL BIOFARMA 40 MG / 2ML AMPUL, 10 ADETBendazac
go.drugbank.com/drugs/DB13501ApprovedWithdrawna small handful of regions may continue to have the medication available for purchase and use either as a topical anti-inflammatory/analgesic cream or eye drop formulation. … Bendazac, however, has since been withdrawn or discontinued in various international regions due to its capability or risk for eliciting hepatotoxicity [A39891, A39892, A39893, L4778] in patients although
Pasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalIt is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Synonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)Products: SIGNIFOR® LAR 20 MG, SIGNIFOR® LAR 40 MGMaralixibat
go.drugbank.com/drugs/DB16226ApprovedInvestigationalIt was granted FDA approval on 29 September 2021. … [A239249] No clinical trials have been performed to assess the efficacy of these treatments for cholestatic pruritus and treatments were given based on a prescriber's clinical experience.
Edotreotide
go.drugbank.com/drugs/DB17969InvestigationalCategories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingFosamprenavir
go.drugbank.com/drugs/DB01319ApprovedInvestigationalFosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Products: TELZIR 700 MG FİLM KAPLI TABLET, 60 ADETPexidartinib
go.drugbank.com/drugs/DB12978ApprovedInvestigational[A182240,L7901] Debilitating symptoms often follow with tenosynovial giant cell tumors, along with a risk of significant functional limitations and a reduced quality of life in patients. … [L7901] While surgical resection is a current standard of care for tenosynovial giant cell tumor, there are tumor types where surgeries are deemed clinically ineffective with a high risk of lifetime
Isopropamide
go.drugbank.com/drugs/DB01625ApprovedVet approvedWithdrawnIt is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.