Edotreotide

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DB17969InvestigationalSmall molecule

Edotreotide: Overview.

Mechanism: Pharmacologically active on Somatostatin receptor type 5, Somatostatin receptor type 2, and Somatostatin receptor
Curator reviewed
Formula / weight: C₆₅H₉₂N₁₄O₁₈S₂ · 1421.65 g/mol (avg)
Also known as: Dotatoc · L-cysteinamide, n-((4,7,10-tris(carboxymetnyl)-1,4,7,10-tetraazacyclodec-1-yl)acetyl)-d-phenylalanyl-l-cysteinyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-threonyl-n-((1r,2r)-2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic(2->7)-disulfide · N-((4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacycoldodec-1-yl)acetyl-d-phenylalanyl-l-cysteinyl-l-tyrosyl-d-tryprophyl-l-lysyl-l-threonyl-n-((1r,2r)-2-hydroxy-1-(hydroxymethyl)propyl)-l-cysteinamide cyclic (2->7)-disulfide
Code names: SMT-487

Resolves to

Compound

UNIIU194AS08HZCAS204318-14-9

Structure

InChIKeyRZHKDBRREKOZEW-UHVHPHPQSA-NSMILES

C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CC2=CNC3=CC=CC=C23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1

Targets

P35346SSTR5P30874SSTR2

What you can answer from here — as of July 08, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

13Clinical trialsPhase, status and sponsor resolved per trial

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with Edotreotide, and which of those have an active Phase 3 trial?

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