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Methylprednisone
go.drugbank.com/drugs/DB12952ApprovedInvestigationalWithdrawnMethylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCortivazol
go.drugbank.com/drugs/DB13003InvestigationalCortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersMacimorelin
go.drugbank.com/drugs/DB13074ApprovedMore specifically, macimorelin is a peptidomimetic growth hormone secretagogue (GHS) that acts as an agonist of GH secretagogue receptor, or ghrelin receptor (GHS-R1a) to dose-dependently increase GH levels … Macimorelin is clinically useful since it displays good stability and oral bioavailability with comparable affinity to ghrelin receptor as its endogenous ligand.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTalarozole
go.drugbank.com/drugs/DB13083InvestigationalTalarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
Categories: Cytochrome P-450 Enzyme InhibitorsLumefantrine co-artemether
go.drugbank.com/drugs/DB13085ApprovedInvestigationalWithdrawnLumefantrine Co-Artemether (Riamet) has been investigated for the treatment of Malaria, Malaria, Falciparum, Malaria in Pregnancy, Uncomplicated Malaria, and Uncomplicated Knowlesi Malaria. Lumefantrine Co-Artemether is a tablet formulat...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFluindione
go.drugbank.com/drugs/DB13136ApprovedWithdrawnFluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. Fluindione has been investigated for...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesParachlorophenol
go.drugbank.com/drugs/DB13154ApprovedWithdrawnP-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible.
Synonyms: p-ChlorophenolTunicamycin
go.drugbank.com/drugs/DB13172ExperimentalTunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes.
Troleandomycin
go.drugbank.com/drugs/DB13179ApprovedA macrolide antibiotic that is similar to erythromycin.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSitafloxacin
go.drugbank.com/drugs/DB13261InvestigationalCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors