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Displaying results 2571 - 2580 of 10000 in total
  1. Drug

    Aluminum chlorohydrex propylene glycol

    go.drugbank.com/drugs/DB11208
    Approved

    Aluminum chlorohydrex propylene glycol is a complex consisting of Aluminum Chorohydrate and propylene glycol (PG).

  2. Drug

    Sodium cation

    go.drugbank.com/drugs/DB14516
    Investigational

    Mixtures: VAMIN 14 IV AMINOASIT SOLÜSYONU, 500 ML, POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML (PVC TORBA) SETLI
  3. Drug

    Tilidine

    go.drugbank.com/drugs/DB13787
    Investigational

    Mixtures: TILICOMP BETA 100/8MG RET, TILICOMP BETA 100/8MG RETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  4. Target

    Galectin-10

    go.drugbank.com/bio_entities/BE0001886
    TargetHumans

    Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg)

    Polypeptides: Galectin-10Synonyms: Gal-10
  5. Target

    Frizzled-10

    go.drugbank.com/bio_entities/BE0020969
    TargetHumans

    Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclea...

    Polypeptides: Frizzled-10Synonyms: Fz-10
  6. Drug

    Verubecestat

    go.drugbank.com/drugs/DB12285
    Investigational

    In the study, administration of Verubecestat at doses of 12, 40 and 60 mg resulted in a dose-dependent and sustained reduction in the levels of Ab40, a measure of BACE1 activity, in CSF from baseline of … 57, 79 and 84 percent, respectively.

  7. Target

    Interleukin-10

    go.drugbank.com/bio_entities/BE0002484
    TargetHumans

    Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetram...

    Polypeptides: Interleukin-10Synonyms: IL-10
  8. Target

    Aquaporin-10

    go.drugbank.com/bio_entities/BE0018706
    TransporterHumans

    Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:11573934, PubMed:12084581, PubMed:217338...

    Polypeptides: Aquaporin-10Synonyms: AQP-10, Aquaglyceroporin-10
  9. Drug

    2-(5-fluoro-pentyl)-2-methyl-malonic-acid

    go.drugbank.com/drugs/DB16029
    Investigational

    2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).

    Synonyms: 2-(5-fluoro-pentyl)-2-methyl-malonic-acid
  10. Drug

    Alglucerase

    go.drugbank.com/drugs/DB00088
    ApprovedWithdrawn

    Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. … Alglucerase was first approved by the FDA in 1991;[A254816] however, it was later discontinued from the market.