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Displaying results 2581 - 2590 of 10000 in total
  1. Drug

    Tosedostat

    go.drugbank.com/drugs/DB11781
    Investigational

    Tosedostat is an inhibitor of the M1 family of aminopeptidases, in particular PuSA, and LTA4 hydrolase. … It has demonstrated anti-tumour activity in a number of models of cancer, both as a single agent and in synergy with cytotoxic agents such as carboplatin and paclitaxel.

  2. Drug

    N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)

    go.drugbank.com/drugs/DB11202
    Approved

    It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties. … Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities and relatively little chance for systemic absorption

    Salts: N-alkyl ethylbenzyl dimethyl ammonium chloride (C12-C14)Mixtures: E-2 Cleanser Sanitizer, All Star Antiseptic Hand Soap E-2
  3. Drug

    Sulfadoxine

    go.drugbank.com/drugs/DB01299
    ApprovedInvestigationalWithdrawn

    A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.

    Mixtures: SULFADOXINA 500 MG + PIRIMETAMINA 25 MG TABLETAS
  4. Drug

    Abametapir

    go.drugbank.com/drugs/DB11932
    Approved

    [A216178] Abametapir was first approved for use in the United States under the brand name Xeglyze on July 27, 2020.[L15163] … The improved ovicidal activity (90-100% _in vitro_) of abemetapir allows for a single administration, in contrast to many other topical treatments, and its novel and relatively non-specific mechanism may

  5. Drug

    Fluorocholine F-18

    go.drugbank.com/drugs/DB15887
    Investigational

    Products: IASOcholine 1 GBq/ml - Injektionslösung, Fluorochol 222 MBq/ml Injektionslösung
  6. Target

    2-oxoglutarate dehydrogenase complex component E1

    go.drugbank.com/bio_entities/BE0000162
    TargetHumans

    2-oxoglutarate dehydrogenase (E1o) component of the 2-oxoglutarate dehydrogenase complex (OGDHC) (PubMed:24495017, PubMed:25210035, PubMed:28435050). … A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to

    Polypeptides: 2-oxoglutarate dehydrogenase complex component E1
  7. Target

    Cytochrome b6-f complex subunit 4

    go.drugbank.com/bio_entities/BE0002473
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex subunit 4Synonyms: Cytochrome b6-f complex subunit IV
  8. Target

    Propionyl-CoA carboxylase complex B subunit

    go.drugbank.com/bio_entities/BE0002846
    TargetStreptomyces coelicolor

    Polypeptides: Propionyl-CoA carboxylase complex B subunit
  9. Target

    Trafficking protein particle complex subunit 3

    go.drugbank.com/bio_entities/BE0003181
    TargetHumans

    May play a role in vesicular transport from endoplasmic reticulum to Golgi

    Polypeptides: Trafficking protein particle complex subunit 3
  10. Target

    High affinity copper uptake protein 1

    go.drugbank.com/bio_entities/BE0003649
    TransporterHumans

    to copper(2+) reduction and probably followed by copper(1+) stabilization (PubMed:30489586). … May function in copper(1+) import from the apical membrane thus may drive intestinal copper absorption (By similarity).

    Polypeptides: High affinity copper uptake protein 1Synonyms: Copper transporter 1