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Sertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalSertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in th...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamineIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: Nu-isdn TabletsTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceuticalTretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is norm...
Mixtures: Throwers Pbc No. 1Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesPerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalPerindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration....
Mixtures: Ag-perindopril / Indapamide, Ag-perindopril / IndapamideProducts: Nb-perindopril, PERINDOPRIL ERB 1A PH 4MGFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, ...
Mixtures: FLUFORTE-N-LIQUIFILMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersPheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine is a first-generation antihistamine in the alkylamine class, similar to brompheniramine and chlorpheniramine. It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. Phe...
Mixtures: THERAFLU® N GRANULADO PARA SOLUCION ORALProducts: FENİRAMİN-PF 45,5 MG/2 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 FLAKONStannous fluoride
go.drugbank.com/drugs/DB11092ApprovedInvestigationalStannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium ...
Products: Crest Pro-Health Sensitive and Gum All Day Protection, Crest Pro-Health Gum and Sensitivity All Day ProtectionInterferon gamma-1b
go.drugbank.com/drugs/DB00033ApprovedInvestigationalHuman Interferon gamma-1b (140 residues), produced from E. coli. … The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray et. al. and not specifically interferon gamma 1b.
Synonyms: IFN-gamma 1b, IFN-gamma-1bCategories: Interferon gamma, Cytochrome P-450 CYP1A2 InhibitorsDiacylglycerol kinase
go.drugbank.com/bio_entities/BE0009935TargetHumansBy controlling the diacylglycerol/DAG-mediated activation of RASGRP3, negatively regulates the Rap1 signaling pathway. … Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:15544348, PubMed:2175712).
Synonyms: DAG kinase alpha, DAG kinase betaBenzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalBenzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain reli...
Products: Nu-benzydamine Oral Rinse, TANTUM VERDE P