Search
Ibuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigationalOnce administered, the R-enantiomer undergoes extensive interconversion to the S-enantiomer _in vivo_ by the activity of the alpha-methylacyl-CoA racemase. … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.
Mixtures: COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML, BIKARAMIN COLD 100/15/1 MG/ 5 ML ŞURUP, 100 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSultamicillin
go.drugbank.com/drugs/DB12127ApprovedWithdrawnSultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Categories: Penicillin GProducts: NOBECID 250 MG/5 ML SUSPANSIYON HAZ. ICIN TOZ 100 ML, SULCID 250 MG/5 ML ORAL SUSPANSIYON HAZ. ICIN KURU TOZ, 100 MLCyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalPrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: Cyclophosphamid Sandoz 100 mg/ml - Konzentrat zur Herstellung einer Injektions-/Infusionslösung, ENDOXAN 500 MG IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADETFurosemide
go.drugbank.com/drugs/DB00695ApprovedInvestigationalVet approvedIn addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients … [L7961] It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body.
Mixtures: SEMİTONE 50/20 MG FILM TABLET, 10 ADET, SEMİTONE 100/20 MG FILM TABLET, 10 ADETSynonyms: 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid, 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acidMenadione
go.drugbank.com/drugs/DB00170ApprovedNutraceuticalA synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Mixtures: LIBAVIT-K 20 MG AMPUL, 5 ADETCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP1A2 InhibitorsTacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalIt reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. … Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection.
Mixtures: Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsLactulose
go.drugbank.com/drugs/DB00581ApprovedInvestigationalLactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic
Synonyms: 4-O-beta-D-Galactopyranosyl-D-fructose, 4-O-beta-D-Galactopyranosyl-D-fructofuranoseProducts: OSMOLAK 667 MG 100 ML SOLUSYON, LAXAMOT 667 MG/ML ŞURUP, 100 MLUrsodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigational[A256272] Due to its hydrophilicity, UDCA is less toxic than [cholic acid] or [chenodeoxycholic acid]. … [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme InducersSynonyms: (3α,5β,7β)-3,7-dihydroxycholan-24-oic acidRivabazumab pegol
go.drugbank.com/drugs/DB17788InvestigationalRivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.
Synonyms: KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA)Itraconazole
go.drugbank.com/drugs/DB01167ApprovedInvestigationalFirst synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. … [A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers.
Mixtures: ITRACONAZOL 33.3 MG + SECNIDAZOL 166.66 MG CÁPSULA, Ciclopirox 3% / Itraconazole 5% / Urea 20%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inhibitors