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Displaying results 251 - 260 of 2828 in total
  1. Drug

    Ivacaftor

    go.drugbank.com/drugs/DB08820
    ApprovedInvestigational

    Alterations in the CFTR gene result in altered production, misfolding, or function of the protein and consequently abnormal fluid and ion transport across cell membranes. … an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, an ion channel involved in the transport

    Categories: Membrane Transport Modulators
  2. Drug

    Fludeoxyglucose (18F)

    go.drugbank.com/drugs/DB09502
    ApprovedInvestigational

    Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PE...

  3. Drug

    Tetraferric tricitrate decahydrate

    go.drugbank.com/drugs/DB14520
    ApprovedInvestigational

    Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. Tetraferric tricitrate decahydrate was granted FDA approval on 5 ...

  4. Drug

    Timbetasin

    go.drugbank.com/drugs/DB19119
    Investigational

    Timbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).

    Synonyms: Ac-ser-asp-lys-pro-asp-met-ala-glu-ile-glu-lys-phe-asp-lys-ser-lys-leu-lys-lys-thr-glu-thr-gln-glu-lys-asn-pro-leu-pro-ser-lys-glu-thr-ile-glu-gln-glu-lys-gln-ala-gly-glu-ser
  5. Target

    Sodium-dependent multivitamin transporter

    go.drugbank.com/bio_entities/BE0000094
    TargetTransporterHumans

    Sodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide (PubMed:10329687, PubMed:15561972, PubMed:19211916, PubMed:20980265, PubMed

    Polypeptides: Sodium-dependent multivitamin transporterSynonyms: Na(+)-dependent multivitamin transporter
  6. Target

    Sodium-dependent dopamine transporter

    go.drugbank.com/bio_entities/BE0009676
    TransporterTargetMouse

    Mediates sodium- and chloride-dependent transport of dopamine (PubMed:10375632, PubMed:12606774). … Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity).

    Polypeptides: Sodium-dependent dopamine transporterSynonyms: DA transporter
  7. Target

    Equilibrative nucleobase transporter 1

    go.drugbank.com/bio_entities/BE0009810
    TransporterHumans

    Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine (PubMed:26455426, PubMed … May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity)

    Polypeptides: Equilibrative nucleobase transporter 1Function: adenine transmembrane transporter activity
  8. Target

    Queuine/queuosine transporter SLC35F2

    go.drugbank.com/bio_entities/BE0024561
    TransporterHumans

    Also involved in choline transport, although the underlying transport mechanism remains to be elucidated (PubMed:40972734)

    Polypeptides: Queuine/queuosine transporter SLC35F2Function: choline transmembrane transporter activity
  9. Drug

    Ferric cation

    go.drugbank.com/drugs/DB13949
    ApprovedWithdrawn

    Iron is an essential element involved in various metabolic processes, including oxygen transport, deoxyribonucleic acid (DNA) synthesis, and energy production in electron transport [A32514].

    Mixtures: FERRITIN COMPLEX
  10. Target

    Protein transport protein SEC31

    go.drugbank.com/bio_entities/BE0009252
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: Protein transport protein SEC31