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Displaying results 251 - 260 of 9337 in total
  1. Drug

    Meperidine

    go.drugbank.com/drugs/DB00454
    ApprovedInvestigational

    A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. … Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  2. Drug

    Amoxicillin

    go.drugbank.com/drugs/DB01060
    ApprovedInvestigationalVet approved

    [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum concentrations than ampicillin. … Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.

    Mixtures: AMOXICILLINA E ACIDO CLAVULANICO KABI, AMOXICILLINA E ACIDO CLAVULANICO KABIProducts: MOPEN, ORMOCYN T-5
  3. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    to be safe and effective in children under the age of 6 years [F4525]. … Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and

    Mixtures: Entex T, Biophex TRProducts: The Medicine Shoppe Chest Congestion Relief, Benylin E Syrup
  4. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States. … The drug is often referred to as the general form, "propoxyphene", however only the dextro-isomer (dextropropoxyphene) has any analgesic effect.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Glimepiride

    go.drugbank.com/drugs/DB00222
    ApprovedInvestigational

    The main effect of SUs is thought to be effective when residual pancreatic β-cells are present,[A177715] as they work by stimulating the release of insulin from the pancreatic beta cells and they are also … of the beta cells.

    Mixtures: METGLITAL LEX 850/4 MG TABLETAS DE LIBERACIÓN PROLONGADA, METGLITAL LEX 850/4 MG TABLETAS DE LIBERACIÓN PROLONGADA
  6. Drug

    Vosoritide

    go.drugbank.com/drugs/DB11928
    ApprovedInvestigational

    [A242273] While the remarkably short half-life of endogenous CNP - 2 to 3 minutes due to its rapid degradation by endopeptidases - makes it ineffective as a therapeutic intervention,[A242273] the development … [L39229] It was approved for use under the brand name Voxzogo (BioMarin Pharmaceutical Inc.) in the EU in August 2021 and the US in November 2021,[L39245,L39241] becoming the first pharmacological intervention

  7. Drug

    Lumacaftor

    go.drugbank.com/drugs/DB09280
    ApprovedInvestigational

    and trafficking of mature protein to the cell surface. … chaperone, aiding the conformational stability of the mutated CFTR protein.

  8. Drug

    Sufentanil

    go.drugbank.com/drugs/DB00708
    ApprovedInvestigational

    Consideration may be made in the future for the use of the sublingual form in the US military in cases where analgesia is required immediately [L4718]. … Also known as _Dsuvia_, the sublingual form is used for the management of acute pain in adults that is severe to warrant the use of an opioid analgesic in certified medically supervised healthcare settings

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  9. Drug

    Apraclonidine

    go.drugbank.com/drugs/DB00964
    ApprovedInvestigational

    Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.

  10. Drug

    Chlorhexidine

    go.drugbank.com/drugs/DB00878
    ApprovedInvestigationalVet approvedWithdrawn

    [L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s. … [L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use

    Mixtures: Re-liv oral lotion, BACCIDINE® SOLUCION ANTISEPTICA DE USO EXTERNOProducts: Ezy-TM, BD E-Z Scrub