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Loratadine
go.drugbank.com/drugs/DB00455ApprovedInvestigationalLoratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Mixtures: Clarinase 5 mg/ 120 mg Retardtabletten, LORATADINA+ PSEUDOEFEDRINA0.5 MG + 6 MG/ML SOLUCION PEDIATRICACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesEtoposide
go.drugbank.com/drugs/DB00773ApprovedInvestigationalA semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexProducts: ETOSID 100 MG/ 5 ML, LASTET 100 MG KAPSUL, 10 ADETBeclomethasone dipropionate
go.drugbank.com/drugs/DB00394ApprovedInvestigationalBeclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and later in a dry powder inhaler and an aqueous nasal spray. … Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone, which is structurally similar to [dexamethasone].
Mixtures: FOSHAL 100 MCG/6 MCG İNHALASYON TOZU, SERT KAPSÜL, 120 ADET, TRYDONİS 87 MCG/5 MCG/9 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 120 DOZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. … [L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence
Mixtures: PIO-ALA 15/600 MG FILM KAPLI TABLET ,30 ADET, PIO-ALA 15/600 MG FILM KAPLI TABLET ,90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigationalRocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. … [Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium.
Products: ANTARİN 100 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET, MUSCOBLOC 100 MG/10 ML İ.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADETMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295]. … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295].
Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, M-FURO FA %0.1 + %2 KREM, 30 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approvedA benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Mixtures: LO-BRUQUINCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigationalMethotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 4-amino-10-methylfolic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acidMiglitol
go.drugbank.com/drugs/DB00491ApprovedMiglitol should be taken at the start of a meal for maximal effect and the effect will depend on the amount of poly and oligosaccharides in the diet.
Mixtures: MEGLITIS 100/500MG EFERVESAN TABLET, 100 TABLET, MEGLITIS 100/850MG EFERVESAN TABLET, 100 TABLETProducts: DIASTABOL 100 MG, MIGLITEC 100 MG TABLET, 100 ADETBeta carotene
go.drugbank.com/drugs/DB06755ApprovedNutraceutical[T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed of two retinyl groups. … [T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS).[L2191]
Mixtures: Folika-MG, ACECAP 20/200/200 MG YUMUŞAK KAPSÜL, 30 ADETCategories: Vitamin A