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Ropivacaine
go.drugbank.com/drugs/DB00296ApprovedInvestigationalRopivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.[L42140]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: (S)-(−)-1-propyl-2',6'-pipecoloxylidide, L-N-n-propylpipecolic acid-2,6-xylidideGallium citrate Ga-67
go.drugbank.com/drugs/DB06784ApprovedAlthough the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation
Products: MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (5 ML), MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (2.5 ML)Rivastigmine
go.drugbank.com/drugs/DB00989ApprovedInvestigationalRivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type.
Synonyms: m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate, (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamateCategories: Compounds used in a research, industrial, or household settingEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalIn a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein. … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 40-O-(2-hydroxyethyl)-rapamycin, 42-O-(2-Hydroxyethyl)rapamycinTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigational[A253717, L43652] Because CTLA-4 is an immune checkpoint that plays a vital role in regulating T cell-mediated immune response, tremelimumab is considered an immune checkpoint inhibitor, which is an emerging … CTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells.
Categories: CTLA-4-directed Blocking AntibodyProducts: Imjudo 25 mg/1.25 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet, Imjudo 300 mg/15 ml İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adetMethylprednisolone hemisuccinate
go.drugbank.com/drugs/DB14644ApprovedInvestigationalA water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP3A InducersProducts: METILPREDNISOLON SOPHARMA 250 MG ENJEKSİYONLUK SOLÜSYON HAZIRLAMAK İÇİN LİYOFİLİZE TOZ İÇEREN AMPUL, 5 ADET, METILPREDNIZOLON SOPHARMA 125 MG IV/IM ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ İÇEREN AMPUL, 5 ADETNizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamineLisinopril
go.drugbank.com/drugs/DB00722ApprovedInvestigational[A184844] Lisinopril was granted FDA approval on 29 December 1987.[L8384] … [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Synonyms: (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline, [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-prolineMixtures: RILACE PLUS 20 MG/25 MG TABLET, 28 TABLET, Co-Lisinostad 20 mg/25 mg - TablettenTobramycin
go.drugbank.com/drugs/DB00684ApprovedInvestigational[A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a variety of forms for administration by inhalation, injection, and external application to … [L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics
Synonyms: O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine, 3'-Deoxykanamycin BMixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, OCUBRAX STERIL GOZ DAMLASI, 5 MLBexarotene
go.drugbank.com/drugs/DB00307ApprovedInvestigationalBexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Synonyms: 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid, p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acidCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 Substrates