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Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine
go.drugbank.com/drugs/DB16757ApprovedThe Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada … [A245819] Plant-based VLPs offer a number of advantages as compared to other vaccine platforms, including speed and ease of manufacturing and increased immunogenicity.
Mequinol
go.drugbank.com/drugs/DB09516ApprovedWithdrawnIt is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture … of antioxidants, pharmaceuticals, plasticizers, and dyestuffs [L993].
RNA-splicing ligase RTCB
go.drugbank.com/bio_entities/BE0004442TargetHumansThese exon ends are then recognized and ligated by RTCB. … The ligation reaction, which requires guanosine triphosphate (GTP) and Mn(2+), proceeds through three metal-dependent steps.
Synonyms: RNA 2',3'-cyclic phosphate and 5'-OH ligaseGrazoprevir
go.drugbank.com/drugs/DB11575ApprovedGrazoprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 and 4 [synthesis]. … Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV).
Mixtures: ZEPATIER FILM-COATED TABLET 50MG/100MGCategories: elbasvir and grazoprevirTrioxsalen
go.drugbank.com/drugs/DB04571ApprovedWithdrawnIt is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema. … Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative obtained from several plants, mainly Psoralea corylifolia.
Products: Trisoralen Tab 5mgClopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigationalClopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. … [A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and
Mixtures: CoPlavix 75/100mg Film-Coated Tablet, COPLAVIX (75/75MG)Categories: Blood and Blood Forming OrgansTechnetium Tc-99m sestamibi
go.drugbank.com/drugs/DB09161ApprovedInvestigationalFollowing intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by the myocardium, parathyroid, and/or breast tissue. … infarction (non-reversible defects); and 2) evaluating myocardial function and developing information for use in patient management decisions.
Categories: Indicators and ReagentsPrednisolone phosphate
go.drugbank.com/drugs/DB14631ApprovedInvestigationalVet approvedPrednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Mixtures: Pred Phos - Brom, Pred Phos-Gati-BromCategories: Hormones, Hormone Substitutes, and Hormone AntagonistsIndacaterol
go.drugbank.com/drugs/DB05039ApprovedInvestigationalIt was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. … Indacaterol is provided as its maleate salt form. Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed.
Categories: indacaterol and mometasone, indacaterol and glycopyrronium bromideIoxaglic acid
go.drugbank.com/drugs/DB09313ApprovedWithdrawnIoxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast agents [L1883]. … , arthrography, cholangiography, urography, and computed tomography [L1889].