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Displaying results 2591 - 2600 of 4188 in total
  1. Drug

    Nitroarginine

    go.drugbank.com/drugs/DB04223
    Investigational

    An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. … Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)

  2. Drug

    ACA 125

    go.drugbank.com/drugs/DB05489
    Investigational

    An IgG1 murine monoclonal anti-idiotype antibody (Ab2), ACA-125, was developed to bind to anti-CA 125 antibodies. ACA-125 mimics the tumor-associated antigen CA-125, which can be detected in about 80% of ovarian carcinomas. This new conc...

  3. Drug

    Atibuclimab

    go.drugbank.com/drugs/DB06546
    Investigational

    Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.

  4. Drug

    AG0301-COVID19

    go.drugbank.com/drugs/DB15856
    Investigational

    The gene transfer method increases the efficiency of gene expression and antibody production capability, garnering a more efficient DNA vaccine product. … The candidate is a plasmid DNA vaccine developed using an intradermal gene transfer method targeting the SARS-CoV-2 spike protein.

  5. Target

    Afadin

    go.drugbank.com/bio_entities/BE0004342
    TargetHumans

    Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs) (By similarity). Nectin- and actin...

    Synonyms: ALL1-fused gene from chromosome 6 protein
  6. Drug

    Human Amniotic Fluid

    go.drugbank.com/drugs/DB15871
    Investigational

    Human amniotic fluid is the liquid surrounding the human embryo and fetus. Physically, the fluid provides protection through cushioning. Chemically, the fluid provides protection through its inherent antibacterial properties. The fluid c...

  7. Target

    Thioredoxin reductase 1, cytoplasmic

    go.drugbank.com/bio_entities/BE0001979
    TargetEnzymeHumans

    Reduces disulfide protein thioredoxin (Trx) to its dithiol-containing form (PubMed:8577704). Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation. A selenocysteine residue at the C-t...

    Synonyms: Gene associated with retinoic and IFN-induced mortality 12 protein, Gene associated with retinoic and interferon-induced mortality 12 protein
  8. Drug

    Arundic acid

    go.drugbank.com/drugs/DB05343
    Investigational

    Arundic acid has been investigated for the treatment of Amyotrophic Lateral Sclerosis (ALS).

  9. Drug

    Flumatinib

    go.drugbank.com/drugs/DB11904
    Investigational

    Flumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic.

  10. Drug

    Acyline

    go.drugbank.com/drugs/DB11906
    Investigational

    Acyline has been investigated for the prevention and treatment of Hypogonadism and Contraception.