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Displaying results 2591 - 2600 of 10000 in total
  1. Drug

    Zolbetuximab

    go.drugbank.com/drugs/DB15118
    ApprovedInvestigational

    from human IgG1. … Zolbetuximab (previously claudiximab)[A264748] is a chimeric cytolytic antibody comprising variable regions derived from mouse anti-human claudin-18 isoform 2 monoclonal antibody and constant regions derived

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents
  2. Drug

    Relacorilant

    go.drugbank.com/drugs/DB14976
    ApprovedInvestigational

    [L56089] Relacorilant was approved by the US FDA on March 25, 2026, for use in combination with [paclitaxel] in patients with certain platinum-resistant cancers.[L56093,L56089] … [A275455,L56096] By competitively blocking the glucocorticoid receptor, relacorilant prevents cortisol from activating anti-apoptotic survival pathways, thereby restoring the efficacy of cytotoxic therapies

  3. Drug

    Oxymetholone

    go.drugbank.com/drugs/DB06412
    ApprovedIllicit

    In 2009, no producers of oxymetholone were identified worldwide (SRI 2009), but it was available from 14 suppliers, including 8 U.S. suppliers (ChemSources 2009). … Anabolic-androgenic steroids (AAS), such as oxymetholone, have been abused by bodybuilders and athletes.

    Categories: Alimentary Tract and Metabolism, Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: Anapolon 50 Tablets 50mg
  4. Drug

    Hypromellose

    go.drugbank.com/drugs/DB11075
    ApprovedInvestigational

    It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations [A24840]. … Hypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water.

    Mixtures: Rohto Sun and Sport, SK Dry Eye Relief
  5. Drug

    Kanamycin

    go.drugbank.com/drugs/DB01172
    ApprovedInvestigationalVet approvedWithdrawn

    Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate. … Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.

    Categories: Alimentary Tract and Metabolism
  6. Drug

    Alteplase

    go.drugbank.com/drugs/DB00009
    ApprovedInvestigational

    [A252340] New thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and [reteplase], have also been developed. … [L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots.

    Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansProducts: ACTILYSE TREATMENT SET 50MG/50ML
  7. Target

    Zinc transporter ZIP10

    go.drugbank.com/bio_entities/BE0009884
    TransporterHumans

    Plays an important for both mature B-cell maintenance and humoral immune responses (By similarity). … When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT (By similarity)

    Synonyms: Zrt- and Irt-like protein 10
  8. Indication

    Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

    go.drugbank.com/conditions/DBCOND0080506
    Drugs: Polatuzumab vedotin
    Synonyms: Malignant lymphoma, large cell, cleaved and noncleaved, Malignant lymphoma - large cell cleaved and non-cleaved
  9. Drug

    Carfilzomib

    go.drugbank.com/drugs/DB08889
    ApprovedInvestigational

    Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: KYPROLIS POWDER FOR SOLUTION FOR INFUSION 60MG/VIAL, Kyprolis (carfilzomib) powder for solution for infusion 60mg/vial
  10. Drug

    Atosiban

    go.drugbank.com/drugs/DB09059
    ApprovedInvestigational

    Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form. … Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor.

    Categories: Amino Acids, Peptides, and Proteins, Genito Urinary System and Sex Hormones