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Cinaciguat
go.drugbank.com/drugs/DB16126InvestigationalCinaciguat is under investigation in clinical trial NCT01067859 (A Phase Iib Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 ΜG/h, 10 ΜG/h) Given Intravenously to Patients
Fosnetupitant
go.drugbank.com/drugs/DB14019ApprovedInvestigationalGenerally, 25% to 30% of patients with a diagnosis of cancer receive chemotherapy as a treatment modality and 70% to 80% of these patients undergoing chemotherapy treatment may experience nausea and vomiting … as major side effects.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 SubstratesPancrelipase protease
go.drugbank.com/drugs/DB11066ApprovedInvestigational[A32742, L2543] The pancrelipase mixture, including pancrelipase protease, was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.[L2510]
Mixtures: Pancrease Mt 10, Creon 10 MinimicrospheresFlurpiridaz F-18
go.drugbank.com/drugs/DB18773Approved[A264519] Flurpiridaz F-18 is an analog of pyridaben, a mitochondrial complex 1 (MC-1) inhibitor.[L51659]
Synonyms: 2-tert-butyl-4-chloro-5-((4-((2-(18f)fluoroethoxy)methyl)phenyl)methoxy)pyridazin-3(2h)-one, 2-tert-butyl-4-chloro-5-[[4-(2-(18F)fluoranylethoxymethyl)phenyl]methoxy]pyridazin-3-oneNabiximols
go.drugbank.com/drugs/DB14011InvestigationalIn Canada, Sativex® has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have not responded … Sativex® has also received a Notice of Compliance with Conditions (NOC/c) for use as an adjunctive treatment for the symptomatic relief of neuropathic pain in adult patients with multiple sclerosis (MS
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsChloride ion
go.drugbank.com/drugs/DB14547InvestigationalMixtures: VAMIN 14 IV AMINOASIT SOLÜSYONU, 500 ML, POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML (PVC TORBA) SETLIElexacaftor
go.drugbank.com/drugs/DB15444ApprovedInvestigational[A187373]-90%[A187361,A187355] of all CF patients. … [L9395] Elexacaftor is considered a next-generation CFTR corrector as it possesses both a different structure and mechanism as compared to first generation correctors like tezacaftor.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 SubstratesStearic acid
go.drugbank.com/drugs/DB03193ApprovedStearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Mixtures: Isa Knox Ageless Serum Makeup Base 10, O Hui Veil Fit Dual Foundation 10Synonyms: C18:0Chlortetracycline
go.drugbank.com/drugs/DB09093ApprovedVet approvedWithdrawnThe organism was named _Streptomyces aureofaciens_ due to its gold-hued color. … It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow.
Mixtures: Aureocort 1 mg/g + 30 mg/g SalbeZoliflodacin
go.drugbank.com/drugs/DB12817ApprovedInvestigational[A274938,L54748] It is indicated as a single-dose oral therapy for the treatment of uncomplicated urogenital gonorrhea.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates