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Bremelanotide
go.drugbank.com/drugs/DB11653Approved[L9635] Bremelanotide was first described in the literature in 2003 when it was known by the investigational code PT-141. … [A179683] Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women.
Cilomilast
go.drugbank.com/drugs/DB03849InvestigationalIt is orally active and acts as a selective Phosphodiesterase-4 inhibitor. … Following four clinical trials, the drug proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile.
Neostigmine
go.drugbank.com/drugs/DB01400ApprovedInvestigationalVet approvedA cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
Oxytetracycline
go.drugbank.com/drugs/DB00595ApprovedInvestigationalVet approvedA tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Dichlorobenzene
go.drugbank.com/drugs/DB14046ApprovedWithdrawnIt is a constituent of the ear-wax removal product Cerumol.
2,2'-Dibenzothiazyl disulfide
go.drugbank.com/drugs/DB14201ApprovedIt is also a known allergen and dermatological sensitizer. Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Cemivameran
go.drugbank.com/drugs/DB19415ApprovedIt is the active ingredient in the 2024-2025 formulation of Pfizer-BioNTech's Comirnaty vaccine.[L36030]
Cyclopentamine
go.drugbank.com/drugs/DB08999ApprovedWithdrawnIt has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine.
Asparagine
go.drugbank.com/drugs/DB00174ApprovedNutraceuticalWithdrawnIt is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Cefmetazole
go.drugbank.com/drugs/DB00274ApprovedIt has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.