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Oxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approvedSir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In t...
Nebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigational[A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985]
Metergoline
go.drugbank.com/drugs/DB13520Approved[A27181] Its use has been studied in various clinical settings such as a treatment for seasonal affective disorder, prolactin hormone regulation due to its inhibitory effect on prolactin release,[A27182
Ripasudil
go.drugbank.com/drugs/DB13165InvestigationalRipasudil is a well tolerated medication that is used when other drugs have been proven to be non-effective or cannot be administered.
DP-b99
go.drugbank.com/drugs/DB05820InvestigationalDP-b99 is a newly developed lipophilic, cell permeable derivative of BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), that is under development as a neuroprotectant for the potential treatment of stroke, head trauma and ...
Lasmiditan
go.drugbank.com/drugs/DB11732ApprovedInvestigational[L9338,L9356] It was also approved by the European Commission on August 17, 2022.[L43997] Traditionally, the triptan class of anti-migraine medications (e.g.
Tigatuzumab
go.drugbank.com/drugs/DB15101InvestigationalTigatuzumab is under investigation in clinical trial NCT00991796 (CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)).
Nimacimab
go.drugbank.com/drugs/DB15115InvestigationalNimacimab is under investigation in clinical trial NCT03261739 (Safety Tolerability, and PK of RYI-018 After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)).
Belrestotug
go.drugbank.com/drugs/DB19066InvestigationalBelrestotug is under investigation in clinical trial NCT05565378 (A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/metastatic Non-small-cell Lung
Emibetuzumab
go.drugbank.com/drugs/DB11849InvestigationalEmibetuzumab has been used in trials studying the treatment of Advanced Cancer, Renal Cell Carcinoma, Hepatocellular Cancer, Gastric Adenocarcinoma, and Non-Small Cell Lung Cancer, among others.