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Displaying results 2651 - 2660 of 2865 in total
  1. Drug

    Chenodeoxycholic acid

    go.drugbank.com/drugs/DB06777
    ApprovedInvestigational

    Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    9-aminocamptothecin

    go.drugbank.com/drugs/DB12515
    Investigational

    Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    Mizolastine

    go.drugbank.com/drugs/DB12523
    Approved

    Mizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  4. Drug

    Ozanimod

    go.drugbank.com/drugs/DB12612
    ApprovedInvestigational

    Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approve...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  5. Drug

    3,5-diiodothyropropionic acid

    go.drugbank.com/drugs/DB12629
    Investigational

    DITPA has been investigated in Congestive Heart Failure.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Givinostat

    go.drugbank.com/drugs/DB12645
    ApprovedInvestigational

    Givinostat is a small molecule histone deacetylase (HDAC) inhibitor. It has been investigated as a treatment for a variety of inflammatory diseases, like Crohn's disease and juvenile idiopathic arthritis, cancers like leukemia and lympho...

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2B6 Inducers
  7. Drug

    Balaglitazone

    go.drugbank.com/drugs/DB12781
    Investigational

    Balaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitors
  8. Drug

    p-Quaterphenyl

    go.drugbank.com/drugs/DB12794
    Investigational

    p-Quaterphenyl has been used in trials studying the treatment of Malaria.

  9. Drug

    Laniquidar

    go.drugbank.com/drugs/DB12799
    Investigational

    Laniquidar has been used in trials studying the treatment of Breast Cancer.

    Categories: P-glycoprotein inhibitors
  10. Drug

    Trifarotene

    go.drugbank.com/drugs/DB12808
    ApprovedInvestigational

    Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to vitamin ...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates