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Cepeginterferon alfa-2B
go.drugbank.com/drugs/DB12814InvestigationalCepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTerpinen-4-ol
go.drugbank.com/drugs/DB12816InvestigationalTerpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesTandospirone
go.drugbank.com/drugs/DB12833InvestigationalTandospirone has been used in trials studying the treatment of Schizophrenia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDihydralazine
go.drugbank.com/drugs/DB12945ApprovedWithdrawnDihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsPexidartinib
go.drugbank.com/drugs/DB12978ApprovedInvestigationalPexidartinib is a selective tyrosine kinase inhibitor that works by inhibiting the colony-stimulating factor (CSF1)/CSF1 receptor pathway. Pexidartinib was originally developed by Daiichi Sankyo, Inc. and it was approved by the FDA in Au...
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesNepicastat
go.drugbank.com/drugs/DB12979InvestigationalNepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.
Categories: P-glycoprotein substratesMephedrone
go.drugbank.com/drugs/DB13108InvestigationalMephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalThe human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the sit...
Mixtures: HAEMATE P, HAEMATE PRhein
go.drugbank.com/drugs/DB13174ExperimentalRhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis . It is known to have hepatoprotective, neph...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsBamifylline
go.drugbank.com/drugs/DB13203InvestigationalBamifylline is a selective A1 adenosine receptor antagonist.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates