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Esomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalat the secretory surface of gastric parietal cells. … Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer.
Synonyms: (S)-omeprazole, (S)-(−)-omeprazoleInternational brands: ES-ODHexetidine
go.drugbank.com/drugs/DB08958ApprovedWithdrawnA bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.
International brands: Isozid-HMixtures: Isozid - H farblos - alkoholische Lösung zur Hautdesinfektion, Isozid - H gefärbt - alkoholische Lösung zur HautdesinfektionMegestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approved17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. … As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: MGA, 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetateMe-4(18F)DG
go.drugbank.com/drugs/DB19207InvestigationalMe-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).
Synonyms: -methyl-4-(F-18)-fluoro-4-deoxy-d-glucopyranoside, Alpha-methyl-4-deoxy-4-((18)f)fluoro-d-glucopyranosideAntithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells. … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients.
Categories: Immunoglobulin G, Increased T Lymphocyte DestructionSynonyms: Lapine T-lymphocyte immune globulin, Anti-T-lymphocyte immune globulin, rabbitTopiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigationalTopiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996. … [L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate, 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamateColistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalIt is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. … Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Synonyms: Polymyxin EMixtures: Coly-Mycin S, Coly-Mycin SCalcium glubionate anhydrous
go.drugbank.com/drugs/DB13142ApprovedCalcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Synonyms: (D-gluconato)(lactobionato)calcium, Calcium D-gluconate lactobionateProducts: CALCIUM SANDOZ 10 ML 1,375 GR AMPUL, 5 ADET, CALCIUM SANDOZ %10 AMPUL, 5 ADETPanitumumab
go.drugbank.com/drugs/DB01269ApprovedInvestigationalPanitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent.
Products: VECTIBIX 20 MG/ML 5 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET, VECTIBIX® 20 MG/ MLPiroxicam
go.drugbank.com/drugs/DB00554ApprovedInvestigationalIts long half-life enables it to be administered once daily. … A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea
Synonyms: 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxidCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates