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Edoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigational(PE) following 5-10 days of initial therapy with a parenteral anticoagulant. … Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor.
Categories: Heterocyclic Compounds, 1-Ring, Blood and Blood Forming OrgansProducts: LIXIANA 15 MG FILM KAPLI TABLET ,10 TABLET, LIXIANA 15 MGLansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigational[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) … Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole.
Mixtures: LACOMBI 15/10 MG KAPSUL, 28 ADET, DUOLANS 15/30 MG SR KAPSUL, 28 ADETCategories: Heterocyclic Compounds, 1-Ring, Alimentary Tract and MetabolismExenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigationalExenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control[L42690].
Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsSynonyms: Exendin 4, Exendin-4Orlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigational[L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in both over-the-counter[L31963] and prescription preparations, depending on the dosage quantity. … It was approved by the FDA for use in combination with a reduced-calorie diet in 1999.
Categories: Alimentary Tract and Metabolism, Cytochrome P-450 CYP3A InducersProducts: FINOBES ® 120 MG., LIPPOX® 120 MG CAPSULASLevosimendan
go.drugbank.com/drugs/DB00922ApprovedInvestigationalWithdrawnLevosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels.
Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 3 InhibitorsProducts: SIMDAX 2.5 MG/ML KONSANTRE INF.COZ.5 ML X FLAKON, 1 ADET, SİMELEV 12,5 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETAmorolfine
go.drugbank.com/drugs/DB09056ApprovedWithdrawnIt is available in the form of a 5% amorolfine nail lacquer used to treat onychomycosis (fungal infection of the toe- and fingernails). … Amorolfine 5% nail lacquer in once or twice weekly applications is 60-71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment (after six months of treatment
Categories: Heterocyclic Compounds, 1-RingProducts: Amorocutan 50 mg/ml wirkstoffhaltiger Nagellack, Exorolfin 50 mg/ml - wirkstoffhaltiger NagellackMefenamic acid
go.drugbank.com/drugs/DB00784ApprovedA non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Categories: Antiinflammatory and Antirheumatic Products, Antiinflammatory and Antirheumatic Products, Non-SteroidsSynonyms: N-(2,3-xylyl)-2-aminobenzoic acid, N-2,3-xylylanthranilic acidNorethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigationalNorethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. … [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol
Synonyms: 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-α-ethynyl-19-norandrost-4-en-17-β-ol-3-oneInternational brands: Primolut-NCidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigational[FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223]
Categories: Heterocyclic Compounds, 1-Ring, Nucleosides and NucleotidesSynonyms: (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid, ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acidBilastine
go.drugbank.com/drugs/DB11591ApprovedBilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Categories: Heterocyclic Compounds, 1-Ring, Decongestants and AntiallergicsProducts: BILAXTEN® 10 MG TABLETA ORODISPERSABLE, Nasitop 10 mg Schmelztabletten