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ISTH0036
go.drugbank.com/drugs/DB18606InvestigationalISTH0036 is a synthetic 14-mer phosphorothioate antisense oligonucleotide directed against TGF-beta2 mRNA
Propylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: PEG-Phen Lubricant Eye Drops, PEG-Phen Ultra Lubricant Eye DropsCategories: Compounds used in a research, industrial, or household settingTacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalIt was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. … It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex.
Mixtures: Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1%, Niacinamide 4% / Tacrolimus 0.1%Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexMidazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigationalMidazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. … [A257153] Midazolam is considered a schedule IV drug in the United States due to the low potential for abuse and low risk of dependence.[L5074]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: N/a, Epistatus 5 mg Lösung zur Anwendung in der MundhöhleSO-101
go.drugbank.com/drugs/DB05345ExperimentalSO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia. … Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day.
Ribavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalProducing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. … The potential use of ribavirin as a treatment for acute myeloid leukemia is currently under investigation.
Mixtures: Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules)Categories: Treatments for Hepatitis CXylometazoline
go.drugbank.com/drugs/DB06694ApprovedXylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels.
Mixtures: Ophtrivin A Ophthalmic Dps, nasic pur NasensprayCategories: Adrenergic alpha-1 Receptor Agonists, Heterocyclic Compounds, 1-RingPatisiran
go.drugbank.com/drugs/DB14582ApprovedIt is marketed as Onpattro which is formulated as patisiran within a liposome envelope for better delivery to the liver, where transthyretin is produced. … Patisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy caused by hereditary transthyretin-mediated amyloidosis [L4220].
Categories: Compounds used in a research, industrial, or household settingDiaPep 277
go.drugbank.com/drugs/DB06651InvestigationalDiaPep 277 is a 24-mer laboratory-made peptide derived from Hsp60(437-460).
Categories: Group I Chaperonins, Diabetes Mellitus, Type 1Chymotrypsin
go.drugbank.com/drugs/DB09375ApprovedInvestigationalVet approvedWithdrawnIt is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. … Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides.
Synonyms: Chymotrypsin A, Chymotrypsin B