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Sasanlimab
go.drugbank.com/drugs/DB18849InvestigationalSasanlimab is under investigation in clinical trial NCT06218069 (Immuno-pet Imaging Responses Administered Immune Checkpoint Inhibitor).
Synonyms: Anti-pd-1 checkpoint inhibitor pf-06801591Ansuvimab
go.drugbank.com/drugs/DB16385Approved[A225933] Ansuvimab, formerly mAb114, is a fully human IgG1 mAb derived from a survivor of the 1995 Kikwit EBOV outbreak 11 years after infection, which displays strong glycan-independent binding to a … [A225943, A225948, A226035] A randomized, controlled trial of four investigational therapies for Ebola virus disease (EVD) in the Democratic Republic of Congo during a previous outbreak that began in 2018
Vildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigational, or a thiazolidinedione in patients with inadequate glycemic control following monotherapy. … Elevated levels of GLP-1 and GIP consequently results in improved glycemic control.[L32803] In clinical trials, vildagliptin has a relatively low risk of hypoglycemia.
Mixtures: Vildagliptin/Metformin 1A Pharma 50 mg/850 mg – Filmtabletten, Vildagliptin/Metformin 1A Pharma 50 mg/1000 mg - FilmtablettenCategories: Glucagon-Like Peptide 1, P-glycoprotein substratesFosaprepitant
go.drugbank.com/drugs/DB06717ApprovedInvestigationalIt is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 AntagonistsProducts: APRITANT IV® 150 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, BRIAN EXDCFBC F-18
go.drugbank.com/drugs/DB14772InvestigationalDCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Synonyms: DCFBC F-18Epicatechin
go.drugbank.com/drugs/DB12039InvestigationalEpicatechin has been used in trials studying the treatment of Pre-diabetes.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTocainide Sodium Channel Cardiac Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126519Drug actionTocainide is an orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. It is used to treat conditions including sustained ventricular tachycardia, ven...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Doravirine
go.drugbank.com/drugs/DB12301ApprovedInvestigational[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). … Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingMolybdenum
go.drugbank.com/drugs/DB11137ApprovedInvestigationalMolybdenum is a chemical element with symbol Mo and atomic number 42. As it is not a naturally occuring free metal on Earth, molybdenum is found only in various oxidation states in minerals. … When complexed with Technetium Tc 99m, molybdenum is used as a radiopharmaceutical agent in diagonistic procedures.
Mixtures: Ribotin-E, Twin Opti PwrFlutemetamol
go.drugbank.com/drugs/DB15058InvestigationalFlutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring