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Displaying results 261 - 270 of 10000 in total
  1. Drug

    Guanethidine

    go.drugbank.com/drugs/DB01170
    ApprovedWithdrawn

    It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. … An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves.

    Categories: guanethidine and diuretics, Antiglaucoma Preparations and MioticsSynonyms: 2-(1-N,N-Heptamethyleneimino)ethylguanidine, N-(2-Perhydroazocin-1-ylethyl)guanidine
  2. Drug

    Hydrocortisone

    go.drugbank.com/drugs/DB00741
    ApprovedInvestigationalVet approved

    Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. … [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.

    Mixtures: DESYN-N, Neo-poly-bac HydroCategories: Alimentary Tract and Metabolism, Sex Hormones and Insulins
  3. Drug

    Fenofibrate

    go.drugbank.com/drugs/DB01039
    ApprovedInvestigational

    Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia. … [L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]

    Mixtures: SIMITRI®145/20MG, Cholib 145mg/20mg Film-Coated TabletCategories: pravastatin and fenofibrate, simvastatin and fenofibrate
  4. Drug

    Pindolol

    go.drugbank.com/drugs/DB00960
    ApprovedInvestigational

    [L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. … Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension.

    Categories: pindolol and other diuretics, Beta Blocking Agents, Non-SelectiveProducts: Nu-pindol Tab 10mg, Nu-pindol Tab 15mg
  5. Drug

    Succinylcholine

    go.drugbank.com/drugs/DB00202
    ApprovedInvestigational

    Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and lasting between four to six minutes, make succinylcholine particularly useful in the setting of short … Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.

    Synonyms: 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)Products: Anectine Nov, Anectine Inj 20mg/ml
  6. Drug

    Cetirizine

    go.drugbank.com/drugs/DB00341
    ApprovedInvestigational

    The prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms. … Allergic rhinitis is associated with multiple missed or unproductive days at work and school, problems with sleep, and other difficulties with day to day activities for many individuals [A175057].

    Mixtures: VERACETAM NF CAPSULAS, ZYRTEC D Allergy and CongestionCategories: Cetirizine and isomer, Decongestants and Antiallergics
  7. Drug

    Thiamine

    go.drugbank.com/drugs/DB00152
    ApprovedInvestigationalNutraceuticalVet approved

    It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. … It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems.

    Mixtures: Thiamine HCl 100mg W C 20mg, APIKOBAL 250MG/250MG/1MG FİLM KAPLI TABLET, 30 ADETCategories: Diet, Food, and Nutrition, Alimentary Tract and Metabolism
  8. Drug

    Bethanechol

    go.drugbank.com/drugs/DB01019
    Approved

    An advantage of bethanechol is that in contrast to acetylcholine, bethanechol is not degraded by cholinesterase allowing its effects to be longer-lasting.[L32539] … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous

    Synonyms: 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminiumProducts: Urecholine Tab 10mg, Urecholine Tab 25mg
  9. Drug

    Escitalopram

    go.drugbank.com/drugs/DB01175
    ApprovedInvestigational

    [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. … [A185726] Escitalopram also differentiates itself from other SSRIs via allosteric action on its target - this may be the mechanism responsible for its observed superior efficacy and faster onset compared

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: NEO ZENTIUS® 10 MG, NEO ZENTIUS® 20 MG COMPRIMIDOS
  10. Drug

    Temazepam

    go.drugbank.com/drugs/DB00231
    Approved

    In particular, before temazepam saw regular prescription use in civilians it was - and still is - employed by the US military as a sedative-hypnotic medication to be taken by soldiers, pilots, etc. to … and approved later on.

    Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesProducts: Co Temazepam Capsules 15mg, REMESTAN MITE 10MG