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Displaying results 2691 - 2700 of 10000 in total
  1. Drug

    Lornoxicam

    go.drugbank.com/drugs/DB06725
    ApprovedInvestigational

    Lornoxicam is approved for use in Japan. … Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug.

    Mixtures: LORNOPAR 8/300 MG EFERVESAN TABLET ,20 ADETCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 Substrates
  2. Drug

    Fomepizole

    go.drugbank.com/drugs/DB01213
    ApprovedVet approved

    Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites. … Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.

    Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesSynonyms: 4-methylpyrazol, 4-methylpyrazole
  3. Target

    5'-nucleotidase

    go.drugbank.com/bio_entities/BE0001096
    TargetEnzymeHumans

    Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:21933152, PubMed:22997138, PubMed:23142347, PubMed:24887587, PubMed:344...

    Polypeptides: 5'-nucleotidaseSynonyms: 5'-NT, 5'-deoxynucleotidase
  4. Target

    Interleukin-5

    go.drugbank.com/bio_entities/BE0001208
    TargetHumans

    Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:2653458, PubMed:9010276).

    Polypeptides: Interleukin-5Synonyms: IL-5
  5. Target

    Kallikrein-5

    go.drugbank.com/bio_entities/BE0010708
    TargetHumans

    May be involved in desquamation

    Polypeptides: Kallikrein-5
  6. Drug

    Ethiodized oil

    go.drugbank.com/drugs/DB00965
    ApprovedInvestigational

    Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. … And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown.

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast ActivityProducts: LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ , 5 ML, LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 10 ML
  7. Drug

    Scorpion (centruroides) immune Fab2 antivenin (equine)

    go.drugbank.com/drugs/DB13905
    Approved

    Envenomation by a scorpion sting can result in serious cardiovascular effects [A32483]. … It was approved by FDA in 2011 and is marketed under the name Anascorp [L2196]. Anascorp is produced from equine IgG antibodies.

    Synonyms: Centruroides (scorpion) Immune F(ab')2 (equine), Centruroides (scorpion) immune F(ab')2 (equine) injectionProducts: ACSERA 5 ML ENJEKSIYONLUK COZELTI KONSANTRESI ICEREN FLAKON, ALVENO AC 10 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET FLAKON+1 ADET ÇÖZÜCÜ AMPUL
  8. Drug

    Levonorgestrel

    go.drugbank.com/drugs/DB00367
    ApprovedInvestigational

    [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. … Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy.

    Mixtures: CYCLO PROGYNOVA N 2MG/0.15, CYCLO PROGYNOVA N 2MG/0.15Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Torasemide

    go.drugbank.com/drugs/DB00214
    ApprovedInvestigational

    Torasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. … [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea, N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide
  10. Drug

    Vardenafil

    go.drugbank.com/drugs/DB00862
    Approved

    Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction. … of cGMP in the smooth muscle cells of the corpus cavernosum.

    Categories: Drugs Used in Erectile Dysfunction, Phosphodiesterase 5 InhibitorsProducts: LEVITRA TABLET 5 mg, Vardenafil 1 A Pharma 5 mg - Filmtabletten