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Reynoutria multiflora root
go.drugbank.com/drugs/DB14295InvestigationalReynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Fo Ti RootAmlexanox
go.drugbank.com/drugs/DB01025ApprovedWithdrawnAmlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. … Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of the general population.
Categories: Drugs for Obstructive Airway DiseasesButabarbital
go.drugbank.com/drugs/DB00237ApprovedIllicitWithdrawnButabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates. … [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.
International brands: Sarisol No. 2Dronabinol
go.drugbank.com/drugs/DB00470ApprovedIllicitInvestigationalDue to its evidence as an appetite stimulant and an anti-nauseant, Dronabinol is approved for use in anorexia associated with weight loss in patients with AIDS and for the treatment of nausea and vomiting … If not provided in their activated form (such as through synthetic forms like Dronabinol or [DB00486]), THC and CBD are obtained through conversion from their precursors, tetrahydrocannabinolic acid-A
Categories: Analgesics, Non-NarcoticRopeginterferon alfa-2b
go.drugbank.com/drugs/DB15119ApprovedInvestigational[A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients. … hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.
Categories: Interferon Type ISynonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2bPenpulimab
go.drugbank.com/drugs/DB16747ApprovedInvestigational[A273843,A273848] Penpulimab-kcqx was approved by the US FDA in April 2025 for the treatment of nasopharyngeal carcinoma in select patients.[L52993,L52998] … The use of an IgG1 backbone - as opposed to an IgG4 backbone as is typical in other anti-PD-1 antibodies like [nivolumab] - is intended to reduce the risk of immune-related adverse events.
Landiolol
go.drugbank.com/drugs/DB12212ApprovedInvestigational[A264733,A264738] First approved in Japan in 2002 [A264758] for the treatment of intraoperative tachyarrhythmias,[A264733] landiolol was approved in Canada in April 2024 [L51938] and in the US in November … for β-1 adrenergic receptors over β-2 receptors.
Prednisolone phosphate
go.drugbank.com/drugs/DB14631ApprovedInvestigationalVet approvedPrednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. … [A187463] Prednisolone phosphate was granted FDA Approval on 19 December 1973.[L14144]
Mixtures: OFTALETYC® NFOnasemnogene abeparvovec
go.drugbank.com/drugs/DB15528ApprovedInvestigational[A187250] As there is no cure for SMA, onasemnogene abeparvovec is a disease-modifying agent that decelerates the disease progression, improves motor function, and manages the symptoms. … Onasemnogene abeparvovec is the first gene therapy that was approved for this indication in the USA.
Floxuridine
go.drugbank.com/drugs/DB00322ApprovedInvestigationalIt has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. … An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution.