Search
TUM012
go.drugbank.com/drugs/DB18652InvestigationalTUM012 is a synthetic polymer PEG conjugated to a phospholipid anchor (2-dipalmitoyl-sn-glycerol-3-phosphatidylethanolamine)
Mecobalamin
go.drugbank.com/drugs/DB03614ApprovedInvestigationalMixtures: L-Methyl-B6-B12, L-Methyl MC NACCategories: Vitamin B Complex, Heterocyclic Compounds, 1-RingDCFBC F-18
go.drugbank.com/drugs/DB14772InvestigationalDCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Synonyms: DCFBC F-18Fexinidazole
go.drugbank.com/drugs/DB12265ApprovedHuman African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by _T. brucei gambiense_ and _T. brucei rhodesiense_, remains a moderate risk (>1/10,000 inhabitants per … Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first (hemolymphatic) stage that progresses to a second (meningoencephalitic) stage in which patients experience progressively
Categories: MATE 2-K Inhibitors, MATE 1 InhibitorsArachidonic Acid Metabolism
smpdb.ca/view/SMP0000075MetabolicThis pathway describes the production and subsequent metabolism of arachidonic acid, an omega-6 fatty acid. In resting cells arachidonic acid is present in the phospholipids (especially phosphatidylethanolamine and phosphatidylcholine) o...
Enzymes: Prostaglandin E synthaseAcetylsalicylic Acid Action Pathway
smpdb.ca/view/SMP0000083Drug actionAcetylsalicylic acid, also known as ASA or aspirin, belongs to a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs). In addition to its anti-inflammatory properties, aspirin also acts as an analgesic, antipyretic and ...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Acetylsalicylic acid · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthaseKetoprofen Action Pathway
smpdb.ca/view/SMP0000085Drug actionKetoprofen (also known as (RS)-2-(3-benzoylphenyl)-propionic acid) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.. Ketoprofen ...
Enzymes: Prostaglandin E synthaseMeloxicam Action Pathway
smpdb.ca/view/SMP0000106Drug actionMeloxicam is a non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic properties. Most NSAIDs, such as ibuprofen and naproxen, are non-selective prostaglandin G/H synthase (a.k.a. cyclooxygenase or COX) inhibitors th...
Enzymes: Prostaglandin E synthaseDiflunisal Action Pathway
smpdb.ca/view/SMP0000289Drug actionDiflunisal (also known as Dolobid) is a prostaglandin G/H synthase inhibitor that can inhibit prostaglandin G/H synthase 1 and 2 which prevent the production of prostaglandin. Therefore, diflunisal can be used for treating prostaglandin-...
Enzymes: Prostaglandin E synthaseFlurbiprofen Action Pathway
smpdb.ca/view/SMP0000697Drug actionFlurbiprofen (also named Ansaid or Froben) is a nonsteroidal anti-inflammatory drugs. It is used for treatment of moderate pain. Flurbiprofen can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 a...
Drugs: Glutamic acid · Glutathione · Flurbiprofen · Dinoprostone · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthase