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Displaying results 2701 - 2710 of 10000 in total
  1. Drug

    Gumelutamide

    go.drugbank.com/drugs/DB21615
    Experimental

    Gumelutamide is a small molecule drug. The usage of the INN stem '-lutamide' in the name indicates that Gumelutamide is a non-steroid antiandrogen.

  2. Drug

    Frevecitinib

    go.drugbank.com/drugs/DB21681
    Investigational

    Frevecitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Frevecitinib is a Janus kinase inhibitor.

  3. Drug

    Odentegravir

    go.drugbank.com/drugs/DB21708
    Experimental

    Odentegravir is a small molecule drug. The usage of the INN stem '-tegravir' in the name indicates that Odentegravir is a HIV integrase inhibitor.

  4. Drug

    Tezacaftor

    go.drugbank.com/drugs/DB11712
    ApprovedInvestigational

    CFTR is active in epithelial cells of organs such as of the lungs, pancreas, liver, digestive system, and reproductive tract. … [A20298,A20299] As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs where it is produced making patients more susceptible to complications such as infections, lung damage

  5. Drug

    Glipizide

    go.drugbank.com/drugs/DB01067
    ApprovedInvestigational

    It was first introduced in 1984 [A179491] and is available in various countries including Canada and the U.S. … [T28] Compared to the first-generation sulfonylureas, such as [tolbutamide] and [chlorpropamide], second-generation sulfonylureas contain a more non-polar side chain in their chemical structure, which

  6. Drug

    Technetium Tc-99m sestamibi

    go.drugbank.com/drugs/DB09161
    ApprovedInvestigational

    The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. … Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by the myocardium, parathyroid, and/or breast tissue.

  7. Drug

    Ceforanide

    go.drugbank.com/drugs/DB00923
    Approved

    Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. … Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Tisagenlecleucel

    go.drugbank.com/drugs/DB13881
    ApprovedInvestigational

    Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy, or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. … Tisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual patient and genetically engineered to express a specific protein called a chimeric

  9. Drug

    Pegcetacoplan

    go.drugbank.com/drugs/DB16694
    ApprovedInvestigational

    [A235000] Pegcetacoplan for subcutaneous use was granted FDA approval on 14 May 2021. … Pegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria (PNH).

  10. Drug

    Ormeloxifene

    go.drugbank.com/drugs/DB13310
    Experimental

    [A251450,A251460] Ormeloxifene is marketed in India as a racemic mixture of the l- (levormeloxifene) and d-isomers (d-ormeloxifene) of _trans_-ormeloxifene. … Ormeloxifene is a third-generation selective estrogen receptor (ER) modulator.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System