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Displaying results 2701 - 2710 of 9886 in total
  1. Drug

    Pitenodil

    go.drugbank.com/drugs/DB21442
    Experimental

    Pitenodil is a small molecule drug. The usage of the INN stem '-dil' in the name indicates that Pitenodil is a vasodilator. Pitenodil has a monoisotopic molecular weight of 353.18 Da.

  2. Drug

    Equilin

    go.drugbank.com/drugs/DB02187
    Experimental

    It has a total of four double bonds in the A- and B-ring. High concentration of equilin is found in the urine of pregnant mares.

  3. Drug

    Amoxapine

    go.drugbank.com/drugs/DB00543
    Approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … See toxicity section below for a complete listing of side effects.

    Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index
  4. Drug

    CCX915

    go.drugbank.com/drugs/DB05159
    Experimental

    CCX915 is developed by ChemoCentryx which targets the chemokine receptor CCR2 and is in phase 1 of clinical trial for the treatment of Multiple Sclerosis and Neurologic Disorders. The CCR2 receptor is thought to be of central importance ...

  5. Drug

    Meclocycline

    go.drugbank.com/drugs/DB13092
    Investigational

    Meclocycline is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment of Oral Mucositis) .

  6. Drug

    Buformin

    go.drugbank.com/drugs/DB04830
    ApprovedWithdrawn

    It was withdrawn from the market in most countries due to a high risk of causing lactic acidosis.

  7. Drug

    Barzuxetan

    go.drugbank.com/drugs/DB21132
    Experimental

    Barzuxetan is a small molecule drug. The usage of the INN stem '-xetan' in the name indicates that Barzuxetan is a chelating agent. Barzuxetan has a monoisotopic molecular weight of 594.2 Da.

    Synonyms: Chx-a''-dtpa
  8. Drug

    Timtraxanib

    go.drugbank.com/drugs/DB21515
    Experimental

    Timtraxanib has a monoisotopic molecular weight of 621.31 Da. … Timtraxanib is a small molecule drug. The usage of the INN stem '-anib' in the name indicates that Timtraxanib is a angiogenesis inhibitor.

  9. Drug

    Guanoxan

    go.drugbank.com/drugs/DB13211
    Approved

    Guanoxan was approved in the UK but was withdrawn from the market due to hepatotoxicity.

  10. Drug

    Clobutinol

    go.drugbank.com/drugs/DB09004
    ApprovedWithdrawn

    Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients.