Search

Displaying results 2701 - 2710 of 10000 in total
  1. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam was given FDA approval on October 16, 1981.[L6148] … [A18125] Alprazolam's adverse effects are generally related to the sedation it can cause.

    Synonyms: 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepineMixtures: NEUPAX DUO-S
  2. Drug

    Bicalutamide

    go.drugbank.com/drugs/DB01128
    ApprovedInvestigational

    It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: BICALUTAMIDE KABI 50 MG FİLM TABLET, 20 ADET, BICALUTAMIDE EG
  3. Drug

    Durvalumab

    go.drugbank.com/drugs/DB11714
    ApprovedInvestigational

    [A192789] Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture,[L12621] durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote … small cell lung cancer (ES-SCLC).

    Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: IMFINZI 500 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, IMFINZI® 50 MG/ML CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN
  4. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium intake) along with pharmacotherapy - it should be noted that treatment with several antihypertensive

    Synonyms: BR1015-2Mixtures: Triplixam 10 mg/2,5 mg/5 mg Filmtabletten, Triplixam 5 mg/1,25 mg/10 mg Filmtabletten
  5. Drug

    Cilofexor

    go.drugbank.com/drugs/DB15168
    Investigational

    Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).

    Synonyms: 2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acidCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Ustekinumab

    go.drugbank.com/drugs/DB05679
    ApprovedInvestigational

    Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. … [A187349] It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice.

    Categories: Interleukin-12 Antagonist, Interleukin-23 AntagonistProducts: STELARA® 90 MG/ML, Stelara Solution for Injection in Pre-Filled Syringe 90 mg/1 mL
  7. Drug

    Treprostinil palmitil

    go.drugbank.com/drugs/DB18792
    Investigational

    Synonyms: Acetic acid, 2-(((1r,2r,3as,9as)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((3s)- 3-hydroxyoctyl)-1h-benz(f)inden-5-yl)oxy)-, hexadecyl ester, Hexadecyl 2-(((1r,2r,3as,9as)-2-hydroxy-1-((s)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1h-cyclopenta(b)naphthalen-5-yl)oxy)acetate
  8. Drug

    Trandolapril

    go.drugbank.com/drugs/DB00519
    ApprovedInvestigational

    It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).

    Mixtures: VERACOMB MR 180/2 MG KAPSÜL, 28 ADET, VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Riluzole

    go.drugbank.com/drugs/DB00740
    ApprovedInvestigational

    A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: RILUZOL - CT 50 MG, RILUTEK 50 MG
  10. Drug

    Fidrisertib

    go.drugbank.com/drugs/DB18064
    Investigational

    Synonyms: (r)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo(1,2-b)pyridazin-4-yl)piperazine-1-carboxylate, 1-piperazinecarboxylic acid, 4-(6-(5-(4-ethoxy-1-(1-methylethyl)-4-piperidinyl)-2-pyridinyl)pyrrolo(1,2-b)pyridazin-4-yl)-, (3r)-tetrahydro-3-furanyl ester