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Ademetionine
go.drugbank.com/drugs/DB00118ApprovedInvestigationalNutraceuticalPhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Mixtures: HEPATAMINE %8 500 ML(SETLI), HEPATAMINE %8 500 ML(SETSIZ)Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2E1 InhibitorsIoxilan
go.drugbank.com/drugs/DB09135ApprovedWithdrawnIoxilan is a tri-iodinated diagnostic contrast agent.
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedSynonyms: N-(2,3-dihydroxypropyl)-N’-(2- hydroxyethyl)-5-[N-(2,3-dihydroxypropyl) acetamido]-2,4,6-triiodoisophthal-amideIcosapent ethyl
go.drugbank.com/drugs/DB08887ApprovedInvestigationalNutraceuticalIcosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). … It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides.
Categories: Fatty Acids, Omega-3Synonyms: E-EPA, (all-Z)-5,8,11,14,17-Eicosapentaenoic acid ethyl esterGuanidine
go.drugbank.com/drugs/DB00536ApprovedIt is also used in laboratory research as a protein denaturant. … A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism.
Categories: MATE 1 Substrates, MATE 2 SubstratesCabozantinib
go.drugbank.com/drugs/DB08875ApprovedInvestigationalCabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. … It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexCeftolozane
go.drugbank.com/drugs/DB09050ApprovedInvestigationalCeftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin. … The manufacturer of this drug is Cubist Pharmaceuticals.
Mixtures: ZERBAXA ® 1 G/0.5 G, ZERBAXA ® 1 G/0.5 GCategories: Heterocyclic Compounds, 2-RingLunsotogene parvec
go.drugbank.com/drugs/DB18278ApprovedInvestigationalLunsotogene parvec is a first-in-class dual adeno-associated virus serotype 1 vector-based gene therapy developed to address an unmet medical need for OTOF-related sensorineural hearing loss. … It is the first gene therapy to be approved under the Commissioner's National Priority Voucher (CNPV) pilot and represents one of the fastest BLA approvals in modern history, with a time between filing
Aclarubicin
go.drugbank.com/drugs/DB11617InvestigationalSynonyms: Aclacinomycin ACategories: Topoisomerase II InhibitorsFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalOnce bound to heparin or HS, the anticoagulant activity of ATIII is potentiated by 1000-fold. Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold. … Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule.
Products: ARIXTRA ® 10MG /0.8 ML, ARIXTRA ® 7.5 MG /0.6 MLIodine povacrylex
go.drugbank.com/drugs/DB09537ApprovedIt is a broad spectrum antiseptic and can provide almost 99.9% antiseptic conditions. It is intended for local use only. … Iodine povacrylex (DuraPrep) is a surgical solution, film-forming iodophor complex that provides fast acting, persistent, broad-spectrum antimicrobial activity.