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Benzyl benzoate
go.drugbank.com/drugs/DB00676ApprovedIt is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. … Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
Categories: Scabicides, Insecticides and Repellents, Antiparasitic Products, Insecticides and RepellentsProducts: BENZOATO DE BENCILO II MK SOLUCION TOPICALevallorphan
go.drugbank.com/drugs/DB00504Approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p683) … An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties.
Ioxitalamic acid
go.drugbank.com/drugs/DB13444ApprovedWithdrawn[A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. … Ioxitalamate is an ionic iodinated contrast medium.[A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg.
Damoctocog alfa pegol
go.drugbank.com/drugs/DB14700ApprovedInvestigationalIn order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized. … [L4576,A38909] This product has been engineered by Bayer[L4576] and a biological license application has been filed with the FDA in August 2017 and FDA approved in August 2018.[F1609]
Cenobamate
go.drugbank.com/drugs/DB06119ApprovedInvestigationalCenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures. … [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA<sub>A</sub> and inhibits voltage gated sodium channels.
Human varicella-zoster immune globulin
go.drugbank.com/drugs/DB11621ApprovedInvestigationalIt is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the disease severity in high-risk patients who … lack evidence of immunity to varicella and for whom varicella vaccine is contraindicated.
Categories: Fluids and Secretions, Amino Acids, Peptides, and ProteinsEflapegrastim
go.drugbank.com/drugs/DB15001ApprovedInvestigational[L43135] In September 2022, eflapegrastim was approved by the US FDA as a prophylactic against infection, as manifested by febrile neutropenia, in patients receiving certain myelosuppressive anti-cancer … [A252320] It typically develops during the first cycle of chemotherapy and is associated with an increased risk of morbidity and mortality.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsEfbemalenograstim alfa
go.drugbank.com/drugs/DB18704ApprovedInvestigationalThis approval was contingent on positive results observed in two pivotal Phase 3 Studies GC-627-04 and GC-627-05 in the US and Europe respectively.[L48887] … alfa can stimulate the production of neutrophils and thus reducing the severity and duration of neutropenia.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSorbitol
go.drugbank.com/drugs/DB01638ApprovedInvestigationalSorbitol occurs naturally and is also produced synthetically from glucose. … It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Mixtures: Cleanse Gut And Colon, INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion)Categories: Indicators and Reagents, Diet, Food, and NutritionEflornithine
go.drugbank.com/drugs/DB06243ApprovedInvestigationalWithdrawn[A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued … This approval is based on positive results obtained from a multi-site, single-arm, externally controlled study of children with high-risk neuroblastoma, where a 52% reduction in the risk of relapse and
Categories: Skin and Mucous Membrane Agents, Amino Acids, Peptides, and Proteins