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Isavuconazonium
go.drugbank.com/drugs/DB06636ApprovedInvestigationalIsovuconazonium has excellent oral bioavailability, predictable pharmacokinetics, and a good safety profile, making it a reasonable alternative to its few other competitors on the market. … This formulation also avoids the use of a cyclodextrin vehicle for solubilization required for intravenous administration of other antifungals such as voriconazole and posaconazole, eliminating concerns
Azficel-T
go.drugbank.com/drugs/DB11051ApprovedWithdrawnAzficel-T is marketed in the US as Laviv for intradermal injection. … Expanded cells are then suspended in a cell medium.
Synonyms: Azficel-TOxacillin
go.drugbank.com/drugs/DB00713ApprovedInvestigationalAn antibiotic similar to [flucloxacillin] used in resistant staphylococci infections.
Products: OXACILINA 1 G POLVO ESTÉRIL PARA RECONSTITUIR A SOLUCIÓN INYECTABLE, OXACILINA 1G POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE.Apadamtase alfa
go.drugbank.com/drugs/DB15164ApprovedInvestigational[A262076] Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible … [A262071] Apadamtase alfa, sold under the brand name Adzynma (ADAMTS13, recombinant-krhn), was approved by the FDA in November 2023 for use as an enzyme replacement therapy in patients with cTTP.
Vorinostat
go.drugbank.com/drugs/DB02546ApprovedInvestigationalIt is the first in a new class of agents known as histone deacetylase inhibitors. … Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease
Technetium Tc-99m sulfur colloid
go.drugbank.com/drugs/DB09397ApprovedThis is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray. … Following injection or oral administration, single photon emission computer tomography (SPECT) imaging is performed using a gamma camera to detect technetium-99m decay.
Categories: Compounds used in a research, industrial, or household settingTriclabendazole
go.drugbank.com/drugs/DB12245ApprovedInvestigational[FDA label, L5452] Fascioliasis is a parasitic infection often caused by the helminth, _Fasciola hepatica_, which is also known as “the common liver fluke” or “the sheep liver fluke” or by _Fasciola … Triclabendazole, manufactured by Novartis pharmaceuticals, is an antihelminthic drug that was approved by the FDA in February 2019 for the treatment of fascioliasis in humans.
Angiotensin II
go.drugbank.com/drugs/DB11842ApprovedInvestigationalAs of December 21, 2017 the FDA approved La Jolla Pharmaceutical's Giapreza (angiotensin II) Injection for Intravenouse Infusion for the indication of acting as a vasoconstrictor to increase blood pressure … As distributive shock is the most common type of shock in the inpatient setting and affects up to one third of patients in the intensive care unit, the FDA determined that there is a need for treatment
Recombinant stabilized RSV A prefusion F antigen
go.drugbank.com/drugs/DB18713ApprovedInvestigationalRecombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. … [L49560] It is the first RSV vaccine approved for use in pregnant patients to prevent RSV in infants.[L49555]
Synonyms: RSV subgroup A stabilized prefusion F protein, Recombinant stabilized RSV A prefusion F antigenErgometrine
go.drugbank.com/drugs/DB01253ApprovedInvestigationalAn ergot alkaloid with uterine and vascular smooth muscle contractile properties.