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Nylidrin
go.drugbank.com/drugs/DB06152ApprovedWithdrawnNylidrin is utilized to treat several disorders that may benefit from increased blood flow (for example, certain mental disorders, blood vessel disease due to diabetes, frostbite, night leg cramps, and
Luteinizing hormone
go.drugbank.com/drugs/DB14741ApprovedInvestigationalMixtures: MENOGON 75 IU Powder and Solvent for solution for InjectionHuman papillomavirus type 16 L1 capsid protein residues 2-471 antigen
go.drugbank.com/drugs/DB10994ApprovedWithdrawnMixtures: CERVARIX SUSPENSION FOR INJECTIONINM005
go.drugbank.com/drugs/DB16499InvestigationalINM005 was under investigation in clinical trials for the treatment of COVID-19. It was studied for pharmacokinetics, efficacy, and safety in a completed trial (NCT04494984). … Additionally, a retrospective cohort study investigated the effectiveness and safety of specific hyperimmune equine serum for severe hospitalized COVID-19 patients (NCT04954235)
Categories: Experimental Unapproved Treatments for COVID-19Cangrelor
go.drugbank.com/drugs/DB06441ApprovedInvestigationalCangrelor was approved by the FDA in June 2015 for intravenous application. … Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors.
Categories: Purinergic P2 Receptor Antagonists, Purinergic P2Y Receptor AntagonistsTolrestat
go.drugbank.com/drugs/DB02383ApprovedWithdrawnTolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. … While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval.
Bimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigational[L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug
Spironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigational[A11837] Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.
Categories: Antihypertensive Agents Indicated for Hypertension, Mineralocorticoid Receptor AntagonistsAmineptine
go.drugbank.com/drugs/DB04836ApprovedIllicitWithdrawnThe Food and Drug Administration suspended the marketing authorisation for Survector in 1999 and France withdrew it from the market, however several developing countries continued to produce it up until
Isoflavone
go.drugbank.com/drugs/DB12007ApprovedInvestigationalWithdrawnIsoflavone is found as one of constituents in oral over-the-counter dietary supplements indicated for improved bone mass density and body fat regulation. … The main soy isoflavones are mostly present in glycosylated forms and include [DB01645], [DB13182], and glycitein, which accounts for approximately 50%, 40%, and 10%, respectively, of the total soybean