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Drugs 2,950
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Displaying results 2721 - 2730 of 2950 in total

Drug
Procainamide
go.drugbank.com/drugs/DB01035
Approved
A derivative of procaine with less CNS action.
Synonyms: p-Aminobenzoic diethylaminoethylamide, p-Amino-N-(2-diethylaminoethyl)benzamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
Drug
Benzylpenicillin
go.drugbank.com/drugs/DB01053
ApprovedInvestigationalVet approved
Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorptio...
Synonyms: PGMixtures: Bicillin A-P Injection Pws, Bicillin A-P Injection Pws
Drug
Tocainide
go.drugbank.com/drugs/DB01056
ApprovedWithdrawn
An antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
Drug
Praziquantel
go.drugbank.com/drugs/DB01058
ApprovedInvestigationalVet approved
Praziquantel is a pyrazino-isoquinolein derivative from the thioxantonic group used as a broad anthelmintic spectrum. Specifically, it is known as a treatment of trematodes and cestodes infections such as schistosomiasis, taeniasis, and ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
Drug
Amoxicillin
go.drugbank.com/drugs/DB01060
ApprovedInvestigationalVet approved
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was gr...
Synonyms: p-Hydroxyampicillin, α-amino-p-hydroxybenzylpenicillinMixtures: AMOXICILLINA E ACIDO CLAVULANICO P-CARE, AMOXICILLINA E ACIDO CLAVULANICO P-CARE
Drug
Melatonin
go.drugbank.com/drugs/DB01065
ApprovedInvestigationalNutraceuticalVet approved
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the ...
Categories: Cytochrome P-450 Substrates, Melatonin Receptor Agonists
Drug
Mequitazine
go.drugbank.com/drugs/DB01071
Investigational
It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
Drug
Primaquine
go.drugbank.com/drugs/DB01087
ApprovedInvestigational
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by tho...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
Drug
Dimethyl sulfoxide
go.drugbank.com/drugs/DB01093
ApprovedInvestigationalVet approved
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue dur...
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2D6 Inhibitors
Drug
Hesperetin
go.drugbank.com/drugs/DB01094
Investigational
Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates