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Mefloquine
go.drugbank.com/drugs/DB00358Approved[A226838] This drug has been the subject of widespread controversy due to concerns regarding neurotoxic effects; product information warns of potential serious neuropsychiatric effects.[A226838,L8953] … Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (DL-ERYTHRO-.ALPHA.-2-PIPERIDYL-2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLINEMETHANOLPentastarch
go.drugbank.com/drugs/DB09111ApprovedWithdrawnPentastarch is an artificial colloid (hydroxyethyl starch derivative). Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation.
Iproclozide
go.drugbank.com/drugs/DB09247ApprovedWithdrawnIproclozide is an irreversible and selective hydrazine class based monoamine oxidase inhibitor (MAOI). … Although it was employed as an antidepressant for a time, the fact that the agent is capable of causing fulminant hepatitis and that its use has been documented as the cause for at least three reported
CYT006-AngQb
go.drugbank.com/drugs/DB05739InvestigationalIt is a unique treatment modality that aims to address the issue of patient compliance by offering convenient dosing schedules due to the long-lasting effect induced by vaccination. … It is designed to instruct the patient’s immune system to produce an antibody response against angiotensin II, a small peptide that causes blood vessels to narrow and results in increased blood pressure
Cusatuzumab
go.drugbank.com/drugs/DB15100InvestigationalAn overexpression of CD70 can result in the proliferation of malignant cells and has been documented in a variety of solid and hematological malignancies. … CD70 is a ligand expressed on the surface of activated lymphocytes and mature dendritic cells that, in its binding to CD27 receptors, plays an important role in cell proliferation and survival.
COVID19 s-vax loaded autologous dendritic cell vaccine
go.drugbank.com/drugs/DB15814ExperimentalThe rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can induce a more prolific immune response. … DC-based vaccines are currently used in cancer therapeutics, and are being tested for COVID-19.
Cianidanol
go.drugbank.com/drugs/DB14086ApprovedInvestigationalWithdrawnAn antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Synonyms: d-Catechin, D-CatecholFloctafenine
go.drugbank.com/drugs/DB08976ApprovedWithdrawnFloctafenine is an anti-inflammatory analgesic similar in action to aspirin. Floctafenine inhibits prostaglandin synthesis.
Polistes fuscatus venom protein
go.drugbank.com/drugs/DB10959ApprovedPolistes fuscatus venom protein is an extract of Polistes fuscatus venom. Polistes fuscatus venom protein is used in allergenic testing.
Polistes metricus venom protein
go.drugbank.com/drugs/DB11029ApprovedPolistes metricus venom protein is an extract of Polistes metricus venom. Polistes metricus venom protein is used in allergenic testing.