Iproclozide

DB09247ApprovedWithdrawnSmall molecule

Iproclozide is an irreversible and selective hydrazine class based monoamine oxidase inhibitor (MAOI). Although it was employed as an antidepressant for a time, the fact that the agent is capable... Although it was employed as an antidepressant for a time, the fact that the agent is capable of causing fulminant hepatitis and that its use has been documented as the cause for at least three...

Chemical structure of Iproclozide
Primary indication
For the treatment of depression.Curator reviewed
Formula / weight
C11H15ClN2O2 · 242.7 g/mol (avg)
Code names
PC-603

Resolves to

Compound
UNII1II9D6CB3JCAS3544-35-2ChEMBLCHEMBL91238ChEBI134988PubChem19063KEGGD07338
Clinical / RWD
ATCN06AF06
Structure
InChIKeyGGECDTUJZOXAAR-UHFFFAOYSA-NSMILESCC(C)NNC(=O)COC1=CC=C(Cl)C=C1

What you can answer from here — as of March 06, 2025

679Drug interactionsStructured to mechanism, not free text
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1ATC codeIncluding every combination product, plus 7 drug categories
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2+ReferencesStructured and connected to the statements they support
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Which companies are running trials of Iproclozide, in which indications and phases, and which of those programs are still active?

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