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Ivacaftor
go.drugbank.com/drugs/DB08820ApprovedInvestigational, an ion channel involved in the transport of chloride and sodium ions across cell membranes. … It was approved by the Food and Drug Administration on January 31, 2012[L768], and by Health Canada in late 2012.
Synonyms: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamideFlupirtine
go.drugbank.com/drugs/DB06623InvestigationalFlupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe. … It is not approved for use in the U.S. or Canada, but is currently in phase II trials for the treatment of fibromyalgia.
Aluminum sesquichlorohydrate
go.drugbank.com/drugs/DB11108ApprovedAluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts [A31171].
Mixtures: Lactovit DEODORANT ROLL-ON MEN INVISIBLE, Lactovit Mens Roll On Antiperspirant DeodorantProducts: Antiperspirant Above Personalities Unique E Modern, Antiperspirant Above Personalities Fierce E SavageAlglucerase
go.drugbank.com/drugs/DB00088ApprovedWithdrawnHuman Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. … Alglucerase was first approved by the FDA in 1991;[A254816] however, it was later discontinued from the market.
Palopegteriparatide
go.drugbank.com/drugs/DB18676ApprovedInvestigational[L51134] Palopegteriparatide was first approved by the EMA on November 17, 2023, for the treatment of hyperparathyroidism.[L51134] On August 8, 2024, palopegteriparatide was also approved by the FDA. … [L51134] PTH(1-34) contains the N-terminal part of the endogenous PTH molecule.
Synonyms: Human parathyroid hormone (PTH) synthetic peptide fragment (1-34), conjugated at the N-terminal amino group via a cleavable linker to O-methylpolyethylene glycol (2 x 20 kDa mPEG); 2-methylalanyl-(1-34, Poly(oxy-1,2-ethanediyl), α-hydro-ω-methoxy-, ether with N-[[[2-[[6-[[1-[3-[[3-(2,3-dihydroxypropoxy)propyl]amino]-3-oxopropyl]-2,5-dioxo-3-pyrrolidinyl]thio]hexyl]amino]ethyl]amino]carbonyl]-2-methylalanyl-L-seryl-L-valyl-L-seryl-L-α-glutamyl-L-isoleSevabertinib
go.drugbank.com/drugs/DB21667ApprovedInvestigational[L54638] It was granted accelerated approval by the FDA on November 19th, 2025.[L54608]
Mucocutaneous Leishmaniasis
go.drugbank.com/conditions/DBCOND0051127Synonyms: Leishmania braziliensis complexMecasermin
go.drugbank.com/drugs/DB01277ApprovedInvestigationalIGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. … The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1.
Sulfadoxine
go.drugbank.com/drugs/DB01299ApprovedInvestigationalWithdrawnA long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
Mixtures: SULFADOXINA 500 MG + PIRIMETAMINA 25 MG TABLETASLactobacillus acidophilus
go.drugbank.com/drugs/DB15823ApprovedInvestigationalMixtures: GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 6 ADET, GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 12 ADETProducts: GINIL COMPRESA VAGINAL